Does computerized cognitive behavioral therapy help people with inflammatory bowel disease? A randomized controlled trial

McCombie, Andrew, Gearry, Richard, Andrews, Jane, Mulder, Roger and Mikocka-Walus, Antonina 2016, Does computerized cognitive behavioral therapy help people with inflammatory bowel disease? A randomized controlled trial, Inflammatory bowel diseases, vol. 22, no. 1, pp. 171-181, doi: 10.1097/MIB.0000000000000567.

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Title Does computerized cognitive behavioral therapy help people with inflammatory bowel disease? A randomized controlled trial
Author(s) McCombie, Andrew
Gearry, Richard
Andrews, Jane
Mulder, Roger
Mikocka-Walus, AntoninaORCID iD for Mikocka-Walus, Antonina
Journal name Inflammatory bowel diseases
Volume number 22
Issue number 1
Start page 171
End page 181
Total pages 11
Publisher Lippincott Williams & Wilkins
Place of publication Philadelphia, Pa.
Publication date 2016-01
ISSN 1078-0998
Keyword(s) Crohn's disease
ulcerative colitis
quality of Life
Summary BACKGROUND: Cognitive behavioral therapy may be useful for improving health-related quality of life (HRQOL) of at least some patients with inflammatory bowel disease (IBD), especially those with psychiatric comorbidities. However, cognitive behavioral therapy can be difficult to access. These difficulties can be overcome by computerized cognitive behavioral therapy (CCBT). This is a randomized controlled trial of a self-administered CCBT intervention for patients with IBD focused on improving HRQOL. It is hypothesized that CCBT completers will have an improved HRQOL relative to people not allocated to CCBT.

METHODS: Patients with IBD were randomly allocated to CCBT (n = 113) versus treatment as usual (n = 86). The IBD Questionnaire at 12 weeks after baseline was the primary outcome, while generic HRQOL, anxiety, depression, coping strategies, perceived stress, and IBD symptoms were secondary outcomes. Outcomes were also measured at 6 months after baseline. Predictors of dropout were also determined.

RESULTS: Twenty-nine CCBT participants (25.7%) completed the CCBT. The IBD Questionnaire was significantly increased at 12 weeks in CCBT completers compared with treatment-as-usual patients (F = 6.38, P = 0.01). Short Form-12 mental score (F = 5.00, P = 0.03) was also significantly better in CCBT compared with treatment-as-usual patients at 12 weeks. These outcomes were not maintained at 6 months. The predictors of dropout were baseline depression, biological use, lower IBD Questionnaire scores, and not having steroids.

CONCLUSIONS: Improvements at 12 weeks after baseline were not maintained at 6 months. Future research should aim to improve adherence rates. Moreover, CCBT may not work for patients with IBD with comorbid depression.
Language eng
DOI 10.1097/MIB.0000000000000567
Field of Research 110399 Clinical Sciences not elsewhere classified
1103 Clinical Sciences
Socio Economic Objective 929999 Health not elsewhere classified
HERDC Research category C1.1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2015, Crohn's & Colitis Foundation of America
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Document type: Journal Article
Collections: Faculty of Health
School of Psychology
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