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Aptamer-mediated siRNA delivery to target colon cancer stem cells

Al Shamaileh, Hadi 2016, Aptamer-mediated siRNA delivery to target colon cancer stem cells, PhD. thesis, School of Medicine, Deakin University.

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Title Aptamer-mediated siRNA delivery to target colon cancer stem cells
Author Al Shamaileh, Hadi
Institution Deakin University
School School of Medicine
Faculty Faculty of Health
Degree type Research doctorate
Degree name PhD.
Thesis advisor Duan Wei
Shigdar Sarah
Date submitted 2016-05
Keyword(s) Cancer
Stem cell research
Autophagy
Summary Cancer stem cells are often referred to as the root of cancer as they drive tumour growth and are resistant to traditional anti-cancer therapies. By using a colon cancer model, targeting the cancer stem cells with aptamers can efficiently kill these cells and prevent tumours from regrowing.
Language eng
Field of Research 111204 - Cancer Therapy (excl. Chemotherapy and Radiation Therapy) 50%
100709 - Nanomedicine 25%
111209 - Solid Tumours 25%
Socio Economic Objective 920102 - Cancer and Related Disorders 80% 970111 - Expanding Knowledge in the Medical and Health Sciences 20%
Description of original xi, 172 pages : illustrations, tables, figures, some coloured
Restricted until 2017-10-25
Copyright notice ┬ęThe author
Persistent URL http://hdl.handle.net/10536/DRO/DU:30088970

Document type: Thesis
Collection: Higher degree theses (citation only)
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Created: Wed, 16 Nov 2016, 11:34:35 EST by Deb Gray

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