The use of near-infrared spectroscopy in understanding skeletal muscle physiology: recent developments

Ferrari, Marco, Muthalib, Makii and Quaresima, Valentina 2011, The use of near-infrared spectroscopy in understanding skeletal muscle physiology: recent developments, Philosophical transactions A: mathematical, physical and engineering sciences, vol. 369, no. 1955, pp. 4577-4590, doi: 10.1098/rsta.2011.0230.

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Title The use of near-infrared spectroscopy in understanding skeletal muscle physiology: recent developments
Author(s) Ferrari, Marco
Muthalib, Makii
Quaresima, Valentina
Journal name Philosophical transactions A: mathematical, physical and engineering sciences
Volume number 369
Issue number 1955
Start page 4577
End page 4590
Total pages 14
Publisher Royal Society Publishing
Place of publication London, Eng.
Publication date 2011-11-28
ISSN 1364-503X
Keyword(s) Arm
Muscle, Skeletal
Oxygen Consumption
Signal Processing, Computer-Assisted
Spectroscopy, Near-Infrared
Time Factors
near-infrared spectroscopy
near-infrared imaging
muscle oxygenation
muscle oxy-haemoglobin saturation
muscle metabolism
Summary This article provides a snapshot of muscle near-infrared spectroscopy (NIRS) at the end of 2010 summarizing the recent literature, offering the present status and perspectives of the NIRS instrumentation and methods, describing the main NIRS studies on skeletal muscle physiology, posing open questions and outlining future directions. So far, different NIRS techniques (e.g. continuous-wave (CW) and spatially, time- and frequency-resolved spectroscopy) have been used for measuring muscle oxygenation during exercise. In the last four years, approximately 160 muscle NIRS articles have been published on different physiological aspects (primarily muscle oxygenation and haemodynamics) of several upper- and lower-limb muscle groups investigated by using mainly two-channel CW and spatially resolved spectroscopy commercial instruments. Unfortunately, in only 15 of these studies were the advantages of using multi-channel instruments exploited. There are still several open questions in the application of NIRS in muscle studies: (i) whether NIRS can be used in subjects with a large fat layer; (ii) the contribution of myoglobin desaturation to the NIRS signal during exercise; (iii) the effect of scattering changes during exercise; and (iv) the effect of changes in skin perfusion, particularly during prolonged exercise. Recommendations for instrumentation advancements and future muscle NIRS studies are provided.
Language eng
DOI 10.1098/rsta.2011.0230
Field of Research 111699 Medical Physiology not elsewhere classified
MD Multidisciplinary
Socio Economic Objective 920116 Skeletal System and Disorders (incl. Arthritis)
HERDC Research category C1.1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2011, The Royal Society
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Document type: Journal Article
Collections: Faculty of Health
School of Psychology
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