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The role of antidepressants in the management of inflammatory bowel disease (IBD): a short report on a clinical case-note audit

Mikocka-Walus, Antonina A., Gordon, Andrea L., Stewart, Benjamin J. and Andrews, Jane M. 2012, The role of antidepressants in the management of inflammatory bowel disease (IBD): a short report on a clinical case-note audit, Journal of psychosomatic research, vol. 72, no. 2, pp. 165-167, doi: 10.1016/j.jpsychores.2011.06.006.

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Title The role of antidepressants in the management of inflammatory bowel disease (IBD): a short report on a clinical case-note audit
Author(s) Mikocka-Walus, Antonina A.ORCID iD for Mikocka-Walus, Antonina A. orcid.org/0000-0003-4864-3956
Gordon, Andrea L.
Stewart, Benjamin J.
Andrews, Jane M.
Journal name Journal of psychosomatic research
Volume number 72
Issue number 2
Start page 165
End page 167
Total pages 3
Publisher Elsevier
Place of publication Amsterdam, The Netherlands
Publication date 2012-02
ISSN 0022-3999
1879-1360
Keyword(s) inflammatory bowel disease
antidepressants
case-note audit
disease activity
mental health
Summary OBJECTIVE: This study sought to determine the frequency of use and types of antidepressants used in IBD patients and to collect data with respect to any effect of antidepressants on the course of IBD in a usual care setting.

METHOD: A case-note audit was conducted at an IBD Service in a public tertiary hospital. Included patients were those diagnosed with IBD by a gastroenterologist; and have had contact with the IBD Service in the last 6months. Descriptive statistics were used to summarise the data.

RESULTS: Overall, 313 patients were eligible and 287 had complete data. Overall, 51 (17.8%) patients were currently taking antidepressants and 71 (24.7%) previously received antidepressants. Eighty-three (28.9%) patients had used an antidepressant at some time. In terms of disease activity while on antidepressants, the majority of patients had inactive disease but presented with what were thought by their clinicians to be functional symptoms.

CONCLUSION: Antidepressants are commonly prescribed in IBD patients. In our cohort, they appear to be mostly used for functional symptoms. The current data do not allow us to judge whether they improve IBD disease activity. Targeted studies are needed to answer this question and to improve practice and patient outcomes.
Language eng
DOI 10.1016/j.jpsychores.2011.06.006
Field of Research 110307 Gastroenterology and Hepatology
110319 Psychiatry (incl Psychotherapy)
Socio Economic Objective 920105 Digestive System Disorders
HERDC Research category C1.1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2011, Elsevier
Persistent URL http://hdl.handle.net/10536/DRO/DU:30090082

Document type: Journal Article
Collection: School of Psychology
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