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Age of onset of obesity and risk of type 2 diabetes

Tanamas, Stephanie K., Wong, Evelyn, Backholer, Kathryn, Abdullah, Asnawi, Wolfe, Rory, Barendregt, Jan and Peeters, Anna 2016, Age of onset of obesity and risk of type 2 diabetes, Australian and New Zealand journal of public health, vol. 40, no. 6, pp. 579-581, doi: 10.1111/1753-6405.12593.

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Title Age of onset of obesity and risk of type 2 diabetes
Author(s) Tanamas, Stephanie K.
Wong, Evelyn
Backholer, KathrynORCID iD for Backholer, Kathryn orcid.org/0000-0002-3323-575X
Abdullah, Asnawi
Wolfe, Rory
Barendregt, Jan
Peeters, AnnaORCID iD for Peeters, Anna orcid.org/0000-0003-4340-9132
Journal name Australian and New Zealand journal of public health
Volume number 40
Issue number 6
Start page 579
End page 581
Total pages 3
Publisher Wiley
Place of publication London, Eng.
Publication date 2016-12
ISSN 1753-6405
Keyword(s) age of onset
body mass index
obese-years
obesity
type 2 diabetes
Summary OBJECTIVE: To compare a simple measure - age of onset of obesity - to an obese-years construct (a product of duration and magnitude of obesity) as risk factors for type 2 diabetes.

METHOD: Participants from the Framingham Heart Study who were not obese and did not have diabetes at baseline were included (n=4,320). The Akaike Information Criterion (AIC) was computed to compare four Cox proportional hazards models with incident diabetes as the outcome and: (i) obese-years; (ii) age of onset of obesity; (iii) body mass index (BMI); and (iv) age of onset of obesity plus magnitude of BMI combined, as exposures.

RESULTS: AIC indicated that the model with obese-years provided a more effective explanation of incidence of type 2 diabetes compared to the remaining three models. Models including age of onset of obesity plus BMI were not appreciably different from the model with BMI alone, except in those aged ≥60.

CONCLUSIONS: While obese-years was the optimal obesity construct to explain risk of type 2 diabetes, age of onset may be a useful, practical addition to current BMI in the elderly.

IMPLICATIONS: Where computation of obese-years is not possible or impractical, age of onset of obesity combined with BMI may provide a useful alternative.
Language eng
DOI 10.1111/1753-6405.12593
Field of Research 111799 Public Health and Health Services not elsewhere classified
1117 Public Health And Health Services
1402 Applied Economics
1605 Policy And Administration
Socio Economic Objective 920104 Diabetes
HERDC Research category C1.1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2016, Public Health Association of Australia
Persistent URL http://hdl.handle.net/10536/DRO/DU:30090309

Document type: Journal Article
Collection: School of Health and Social Development
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Created: Wed, 21 Dec 2016, 06:17:45 EST

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