Does intentional weight loss improve daytime sleepiness? A systematic review and meta-analysis

Ng, Winda Liviya, Stevenson, Christopher E, Wong, Emily, Tanamas, S, Boelsen-Robinson, Tara, Shaw, JE, Naughton, MT, Dixon, J and Peeters, Anna 2017, Does intentional weight loss improve daytime sleepiness? A systematic review and meta-analysis, Obesity reviews, vol. 18, no. 4, pp. 460-475, doi: 10.1111/obr.12498.

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Title Does intentional weight loss improve daytime sleepiness? A systematic review and meta-analysis
Author(s) Ng, Winda Liviya
Stevenson, Christopher EORCID iD for Stevenson, Christopher E
Wong, Emily
Tanamas, S
Boelsen-Robinson, TaraORCID iD for Boelsen-Robinson, Tara
Shaw, JE
Naughton, MT
Dixon, J
Peeters, AnnaORCID iD for Peeters, Anna
Journal name Obesity reviews
Volume number 18
Issue number 4
Start page 460
End page 475
Total pages 16
Publisher Wiley-Blackwell
Place of publication London, Eng.
Publication date 2017-04
ISSN 1467-7881
Keyword(s) Daytime sleepiness
weight loss
Science & Technology
Life Sciences & Biomedicine
Endocrinology & Metabolism
Positive airway pressure
Life-style intervention
Randomized controlled-trial
Apnea syndrome
Gastric bypass
Hypoventilation syndrome
Bariatric surgery
Hypopnea syndrome
Loss program
Summary Obesity is associated with excessive daytime sleepiness, but its causality remains unclear. We aimed to assess the extent to which intentional weight loss affects daytime sleepiness. Electronic databases were searched through 24 October 2016. Studies involving overweight or obese adults, a weight loss intervention and repeated valid measures of daytime sleepiness were included in the review. Two independent reviewers extracted data on study characteristics, main outcome (change in daytime sleepiness score standardized by standard deviation of baseline sleepiness scores), potential mediators (e.g. amount of weight loss and change in apnoea-hypopnoea index) and other co-factors (e.g. baseline demographics). Forty-two studies were included in the review. Fifteen before-and-after studies on surgical weight loss interventions showed large improvements in daytime sleepiness, with a standardized effect size of -0.97 (95% confidence interval [CI] -1.21 to -0.72). Twenty-seven studies on non-surgical weight loss interventions showed small-to-moderate improvement in daytime sleepiness, with a standardized effect size of -0.40 (95%CI -0.52 to -0.27), with no difference between controlled and before-and-after studies. We found a nonlinear association between amount of weight loss and change in daytime sleepiness. This review suggests that weight loss interventions improve daytime sleepiness, with a clear dose-response relationship. This supports the previously hypothesized causal effect of obesity on daytime sleepiness. It is important to assess and manage daytime sleepiness in obese patients.
Language eng
DOI 10.1111/obr.12498
Field of Research 111799 Public Health and Health Services not elsewhere classified
11 Medical And Health Sciences
17 Psychology And Cognitive Sciences
Socio Economic Objective 920401 Behaviour and Health
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2017, World Obesity Federation
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