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The effect of functional gastrointestinal disorders on psychological comorbidity and quality of life in patients with inflammatory bowel disease

Mikocka-Walus, A.A., Turnbull, D.A., Andrews, J.M., Moulding, N.T. and Holtmann, G.J. 2008, The effect of functional gastrointestinal disorders on psychological comorbidity and quality of life in patients with inflammatory bowel disease, Alimentary pharmacology and therapeutics, vol. 28, no. 4, pp. 475-483, doi: 10.1111/j.1365-2036.2008.03754.x.

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Title The effect of functional gastrointestinal disorders on psychological comorbidity and quality of life in patients with inflammatory bowel disease
Author(s) Mikocka-Walus, A.A.ORCID iD for Mikocka-Walus, A.A. orcid.org/0000-0003-4864-3956
Turnbull, D.A.
Andrews, J.M.
Moulding, N.T.
Holtmann, G.J.
Journal name Alimentary pharmacology and therapeutics
Volume number 28
Issue number 4
Start page 475
End page 483
Total pages 9
Publisher Wiley-Blackwell Publishing
Place of publication Chichester, Eng.
Publication date 2008-08
ISSN 0269-2813
1365-2036
Keyword(s) Adult
Aged
Aged, 80 and over
Anxiety Disorders
Depressive Disorder
Female
Humans
Inflammatory Bowel Diseases
Male
Middle Aged
Quality of Life
Surveys and Questionnaires
Summary BACKGROUND: Symptoms of functional gastrointestinal disorders (FGIDs) are common in patients with inflammatory bowel disease (IBD). Psychological comorbidities of anxiety and depression are also highly prevalent in IBD. AIM: To quantify the burden of FGIDs in a hospital-based cohort of patients with IBD and to determine whether there is any inter-relationship between the presence and number of FGIDs and patients' quality of life or psychological status.

METHODS: A cross-sectional survey of 61 out-patients was performed. Data on psychological status, quality of life, disease activity and functional symptoms according to Rome III criteria were collected.

RESULTS: Overall, 49 (80%) participants met Rome III criteria for a functional bowel disorder and 52% of participants met criteria for more than one FGID. Participants with no FGID had significantly better physical quality of life than those with more than two FGIDs (P = 0.025). However, there was no relationship among the number of FGIDs, mental quality of life, anxiety or depression.

CONCLUSIONS: Functional gastrointestinal disorders are highly prevalent in out-patients with IBD. Somewhat unexpectedly, the presence of anxiety and/or depression did not appear to correlate with either the presence or the number of FGIDs.
Language eng
DOI 10.1111/j.1365-2036.2008.03754.x
Field of Research 110307 Gastroenterology and Hepatology
170106 Health, Clinical and Counselling Psychology
111714 Mental Health
1103 Clinical Sciences
1115 Pharmacology And Pharmaceutical Sciences
Socio Economic Objective 920105 Digestive System Disorders
HERDC Research category C1.1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2008, The Authors
Persistent URL http://hdl.handle.net/10536/DRO/DU:30091004

Document type: Journal Article
Collection: School of Psychology
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