Cognitive-behavioural therapy for inflammatory bowel disease: 24-month data from a randomised controlled trial

Mikocka-Walus, Antonina, Bampton, Peter, Hetzel, David, Hughes, Patrick, Esterman, Adrian and Andrews, Jane M. 2017, Cognitive-behavioural therapy for inflammatory bowel disease: 24-month data from a randomised controlled trial, International journal of behavioral medicine, vol. 24, no. 1, pp. 127-135, doi: 10.1007/s12529-016-9580-9.

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Title Cognitive-behavioural therapy for inflammatory bowel disease: 24-month data from a randomised controlled trial
Author(s) Mikocka-Walus, AntoninaORCID iD for Mikocka-Walus, Antonina
Bampton, Peter
Hetzel, David
Hughes, Patrick
Esterman, Adrian
Andrews, Jane M.
Journal name International journal of behavioral medicine
Volume number 24
Issue number 1
Start page 127
End page 135
Total pages 9
Publisher Springer
Place of publication New York, N.Y.
Publication date 2017-02
ISSN 1070-5503
Keyword(s) cognitive-behavioural therapy
disease course
inflammatory bowel disease
Summary PURPOSE: There is ongoing controversy on the effectiveness of psychotherapy in inflammatory bowel disease (IBD). In the few small studies, cognitive-behavioural therapy (CBT) has been shown to alleviate symptoms of anxiety or depression. However, there is little research on the impact of CBT on physical outcomes in IBD and no studies on long-term effectiveness of CBT. METHODS: The present two-arm pragmatic randomised controlled trial aimed to establish the impact of CBT on disease course after 24 months of observation. The study compared standard care plus CBT (+CBT) with standard care alone (SC). CBT was delivered over 10 weeks, face-to-face (F2F) or online (cCBT). The data were analysed using linear mixed-effects models. RESULTS: CBT did not significantly influence disease activity as measured by disease activity indices at 24 months (Crohn's Disease Activity Index (CDAI), p = 0.92; Simple Clinical Colitis Activity Index (SCCAI), p = 0.88) or blood parameters (C-reactive protein (CRP), p < 0.62; haemoglobin (Hb), p = 0.77; platelet, p = 0.64; white cell count (WCC), p = 0.59) nor did CBT significantly affect mental health, coping or quality of life (all p > 0.05). CONCLUSIONS: Therefore, we conclude that CBT does not influence the course of IBD over 24 months. Given the high rate of attrition, particularly in the CBT group, future trials should consider a personalised approach to psychotherapy, perhaps combining online and one-to-one therapist time.
Language eng
DOI 10.1007/s12529-016-9580-9
Field of Research 170106 Health, Clinical and Counselling Psychology
110307 Gastroenterology and Hepatology
110319 Psychiatry (incl Psychotherapy)
1701 Psychology
1117 Public Health And Health Services
Socio Economic Objective 920105 Digestive System Disorders
HERDC Research category C1.1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2016, The Authors
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Document type: Journal Article
Collection: School of Psychology
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