Primary motor cortex excitability Is modulated during the mental simulation of hand movement

Hyde, Christian, Fuelscher, Ian, Lum, Jarrad A.G., Williams, Jacqueline, He, Jason and Enticott, Peter 2017, Primary motor cortex excitability Is modulated during the mental simulation of hand movement, Journal of the International Neuropsychological Society, vol. 23, no. 2, pp. 185-193, doi: 10.1017/S1355617717000029.

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Title Primary motor cortex excitability Is modulated during the mental simulation of hand movement
Author(s) Hyde, ChristianORCID iD for Hyde, Christian
Fuelscher, IanORCID iD for Fuelscher, Ian
Lum, Jarrad A.G.ORCID iD for Lum, Jarrad A.G.
Williams, Jacqueline
He, Jason
Enticott, PeterORCID iD for Enticott, Peter
Journal name Journal of the International Neuropsychological Society
Volume number 23
Issue number 2
Start page 185
End page 193
Total pages 9
Publisher Cambridge University Press
Place of publication Cambridge, Eng.
Publication date 2017-02-16
ISSN 1355-6177
Keyword(s) motor imagery
motor cognition
corticospinal excitability
hand laterality task
hand rotation task
Summary Objectives: It is unclear whether the primary motor cortex (PMC) is involved in the mental simulation of movement [i.e., motor imagery (MI)]. The present study aimed to clarify PMC involvement using a highly novel adaptation of the hand laterality task (HLT). Methods: Participants were administered single-pulse transcranial magnetic stimulation (TMS) to the hand area of the left PMC (hPMC) at either 50 ms, 400 ms, or 650 ms post stimulus presentation. Motor-evoked potentials (MEPs) were recorded from the right first dorsal interosseous via electromyography. To avoid the confound of gross motor response, participant response (indicating left or right hand) was recorded via eye tracking. Participants were 22 healthy adults (18 to 36 years), 16 whose behavioral profile on the HLT was consistent with the use of a MI strategy (MI users). Results: hPMC excitability increased significantly during HLT performance for MI users, evidenced by significantly larger right hand MEPs following single-pulse TMS 50 ms, 400 ms, and 650 ms post stimulus presentation relative to baseline. Subsequent analysis showed that hPMC excitability was greater for more complex simulated hand movements, where hand MEPs at 50 ms were larger for biomechanically awkward movements (i.e., hands requiring lateral rotation) compared to simpler movements (i.e., hands requiring medial rotation). Conclusions: These findings provide support for the modulation of PMC excitability during the HLT attributable to MI, and may indicate a role for the PMC during MI.
Language eng
DOI 10.1017/S1355617717000029
Field of Research 170101 Biological Psychology (Neuropsychology, Psychopharmacology, Physiological Psychology)
11 Medical And Health Sciences
17 Psychology And Cognitive Sciences
Socio Economic Objective 970117 Expanding Knowledge in Psychology and Cognitive Sciences
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2017, International Neuropsychological Society
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Document type: Journal Article
Collections: Faculty of Health
School of Psychology
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