Structural insights into how irreversible inhibitors can overcome drug resistance in EGFR.

Michalczyk, Agnieszka, Klüter, S, Rode, HB, Simard, JR, Grütter, C, Rabiller, M and Rauh, D 2008, Structural insights into how irreversible inhibitors can overcome drug resistance in EGFR., Bioorganic & Medicinal Chemistry, vol. 16, no. 7, pp. 3482-3488, doi: 10.1016/j.bmc.2008.02.053.

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Title Structural insights into how irreversible inhibitors can overcome drug resistance in EGFR.
Author(s) Michalczyk, AgnieszkaORCID iD for Michalczyk, Agnieszka orcid.org/0000-0001-5716-0783
Klüter, S
Rode, HB
Simard, JR
Grütter, C
Rabiller, M
Rauh, D
Journal name Bioorganic & Medicinal Chemistry
Volume number 16
Issue number 7
Start page 3482
End page 3488
Total pages 7
Publisher Elsevier
Place of publication England
Publication date 2008-04-01
ISSN 0968-0896
1464-3391
Keyword(s) Crystallography, X-Ray
Drug Resistance
Erlotinib Hydrochloride
Models, Molecular
Molecular Structure
Mutation
Protein Kinase Inhibitors
Quinazolines
Receptor, Epidermal Growth Factor
Structure-Activity Relationship
Language eng
DOI 10.1016/j.bmc.2008.02.053
Field of Research 0304 Medicinal And Biomolecular Chemistry
1115 Pharmacology And Pharmaceutical Sciences
0305 Organic Chemistry
HERDC Research category CN.1 Other journal article
Persistent URL http://hdl.handle.net/10536/DRO/DU:30095224

Document type: Journal Article
Collection: School of Life and Environmental Sciences
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