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A modified Mediterranean dietary intervention for adults with major depression: dietary protocol and feasibility data from the SMILES trial

Opie, Rachelle S., O'Neil, Adrienne, Jacka, Felice N., Pizzinga, Josephine and Itsiopoulos, Catherine 2018, A modified Mediterranean dietary intervention for adults with major depression: dietary protocol and feasibility data from the SMILES trial, Nutritional neuroscience, vol. 21, no. 7, pp. 487-501, doi: 10.1080/1028415X.2017.1312841.

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Title A modified Mediterranean dietary intervention for adults with major depression: dietary protocol and feasibility data from the SMILES trial
Author(s) Opie, Rachelle S.
O'Neil, Adrienne
Jacka, Felice N.ORCID iD for Jacka, Felice N. orcid.org/0000-0002-9825-0328
Pizzinga, Josephine
Itsiopoulos, Catherine
Journal name Nutritional neuroscience
Volume number 21
Issue number 7
Start page 487
End page 501
Total pages 15
Publisher Taylor & Francis
Place of publication Abingdon, Eng.
Publication date 2018
ISSN 1476-8305
Keyword(s) Depression
Dietary intervention
Dietitian
Modified Mediterranean diet
Randomized controlled trial
Summary Background: The SMILES trial was the first randomized controlled trial (RCT) explicitly designed to evaluate a dietary intervention, conducted by qualified dietitians, for reducing depressive symptomatology in adults with clinical depression.

Objectives: Here we detail the development of the prescribed diet (modified Mediterranean diet (ModiMedDiet)) for individuals with major depressive disorders (MDDs) that was designed specifically for the SMILES trial. We also present data demonstrating the extent to which this intervention achieved improvements in diet quality.

Methods: The ModiMedDiet was designed using a combination of existing dietary guidelines and scientific evidence from the emerging field of nutritional psychiatric epidemiology. Sixty-seven community dwelling individuals (Melbourne, Australia) aged 18 years or over, with current poor quality diets, and MDDs were enrolled into the SMILES trial. A retention rate of 93.9 and 73.5% was observed for the dietary intervention and social support control group, respectively. The dietary intervention (ModiMedDiet) consisted of seven individual nutrition counselling sessions delivered by a qualified dietitian. The control condition comprised a social support protocol matched to the same visit schedule and length.

Results: This manuscript details the first prescriptive individualized dietary intervention delivered by dietitians for adults with major depression. Significant improvements in dietary quality were observed among individuals randomized to the ModiMedDiet group. These dietary improvements were also found to be associated with changes in depressive symptoms.
Language eng
DOI 10.1080/1028415X.2017.1312841
Field of Research 111199 Nutrition and Dietetics not elsewhere classified
11 Medical And Health Sciences
Socio Economic Objective 929999 Health not elsewhere classified
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2017, The Authors
Free to Read? Yes
Use Rights Creative Commons Attribution Non-Commercial No-Derivatives licence
Persistent URL http://hdl.handle.net/10536/DRO/DU:30096024

Document type: Journal Article
Collections: Faculty of Health
School of Medicine
Open Access Collection
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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.