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Progress on Azadirachta indica based biopesticides in replacing synthetic toxic pesticides

Chaudhary, Suman, Kanwar, Rupinder K, Sehgal, Alka, Cahill, David M., Barrow, Colin J., Sehgal, Rakesh and Kanwar, Jagat R. 2017, Progress on Azadirachta indica based biopesticides in replacing synthetic toxic pesticides, Frontiers in plant science, vol. 8, pp. 1-13, doi: 10.3389/fpls.2017.00610.

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Title Progress on Azadirachta indica based biopesticides in replacing synthetic toxic pesticides
Formatted title Progress on Azadirachta indica based biopesticides in replacing synthetic toxic pesticides
Author(s) Chaudhary, Suman
Kanwar, Rupinder K
Sehgal, Alka
Cahill, David M.ORCID iD for Cahill, David M. orcid.org/0000-0002-2556-0528
Barrow, Colin J.ORCID iD for Barrow, Colin J. orcid.org/0000-0002-2153-7267
Sehgal, Rakesh
Kanwar, Jagat R.ORCID iD for Kanwar, Jagat R. orcid.org/0000-0003-3728-9568
Journal name Frontiers in plant science
Volume number 8
Article ID 610
Start page 1
End page 13
Total pages 13
Publisher Frontiers Media
Place of publication Lausanne, Switzerland
Publication date 2017-05
ISSN 1664-462X
Keyword(s) Azadirachta indica
agro-medicinal components
azadirachtin
biopesticide
nanocarriers
pesticides
sustained delivery
Science & Technology
Life Sciences & Biomedicine
Plant Sciences
Azadirachtaindica
agro-medicinalcomponents
NEEM LEAF GLYCOPROTEIN
PROPHYLACTIC GROWTH-INHIBITION
MURINE EHRLICH CARCINOMA
AGRICULTURAL HEALTH
CANCER INCIDENCE
CELL-PROLIFERATION
M2 MACROPHAGES
SEED KERNEL
T-CELLS
OIL
Summary Over the years, extensive use of commercially available synthetic pesticides against phytophagous insects has led to their bioaccumulation in the environment causing increased resistance and reduction in soil biodiversity. Further, 90% of the applied pesticides enter the various environmental resources as a result of run-off, exposing the farmers as well as consumers of the agricultural produce to severe health issues. Therefore, growing attention has been given toward the development of alternate environmentally friendly pesticides/insecticides that would aid an efficient pest management system and also prevent chronic exposures leading to diseases. One such strategy is, the use of neem plant's (Binomial name: Azadirachta indica) active ingredients which exhibit agro-medicinal properties conferring insecticidal as well as immunomodulatory and anti-cancer properties. The most prominent constituent of neem is azadirachtin, which has been established as a pivotal insecticidal ingredient. It acts as an antifeedant, repellent, and repugnant agent and induces sterility in insects by preventing oviposition and interrupting sperm production in males. This review discusses, key neem pesticidal components, their active functional ingredients along with recent strategies on employing nanocarriers, to provide controlled release of the active ingredients and to improve their stability and sustainability.
Language eng
DOI 10.3389/fpls.2017.00610
Field of Research 070308 Crop and Pasture Protection (Pests, Diseases and Weeds)
100202 Biological Control
050205 Environmental Management
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2017, The Authors
Free to Read? Yes
Use Rights Creative Commons Attribution licence
Persistent URL http://hdl.handle.net/10536/DRO/DU:30097420

Document type: Journal Article
Collections: School of Medicine
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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.