Development of a bifunctional aptamer targeting the transferrin receptor and epithelial cell adhesion molecule (EpCAM) for the treatment of brain cancer metastases

Macdonald, Joanna, Henri, Justin, Goodman, Lynda, Xiang, Dongxi, Duan, Wei and Shigdar, Sarah 2017, Development of a bifunctional aptamer targeting the transferrin receptor and epithelial cell adhesion molecule (EpCAM) for the treatment of brain cancer metastases, ACS chemical neuroscience, vol. 8, no. 4, pp. 777-784, doi: 10.1021/acschemneuro.6b00369.

Attached Files
Name Description MIMEType Size Downloads

Title Development of a bifunctional aptamer targeting the transferrin receptor and epithelial cell adhesion molecule (EpCAM) for the treatment of brain cancer metastases
Author(s) Macdonald, Joanna
Henri, Justin
Goodman, Lynda
Xiang, Dongxi
Duan, WeiORCID iD for Duan, Wei orcid.org/0000-0001-5782-9184
Shigdar, SarahORCID iD for Shigdar, Sarah orcid.org/0000-0001-8084-8447
Journal name ACS chemical neuroscience
Volume number 8
Issue number 4
Start page 777
End page 784
Total pages 8
Publisher American Chemical Society
Place of publication Washington, D.C.
Publication date 2017-04-19
ISSN 1948-7193
Keyword(s) Aptamer
Bifunctional
Blood−brain barrier
Epithelial cell adhesion molecule (EpCAM)
Receptor mediated transcytosis
Transferrin receptor
Animals
Aptamers, Nucleotide
Brain Neoplasms
Cell Line
Drug Delivery Systems
Epithelial Cell Adhesion Molecule
Humans
Mice, Inbred NOD
Mice, SCID
Microscopy, Confocal
Neoplasm Metastasis
Receptors, Transferrin
Transcytosis
Science & Technology
Life Sciences & Biomedicine
Biochemistry & Molecular Biology
Chemistry, Medicinal
Neurosciences
Pharmacology & Pharmacy
Neurosciences & Neurology
Language eng
DOI 10.1021/acschemneuro.6b00369
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2016, American Chemical Society
Persistent URL http://hdl.handle.net/10536/DRO/DU:30099145

Document type: Journal Article
Collections: Faculty of Health
School of Medicine
Connect to link resolver
 
Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved.

Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 31 times in TR Web of Science
Scopus Citation Count Cited 31 times in Scopus
Google Scholar Search Google Scholar
Access Statistics: 347 Abstract Views, 1 File Downloads  -  Detailed Statistics
Created: Mon, 24 Jul 2017, 09:27:53 EST

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.