Role of P-glycoprotein in the intestinal absorption of glabridin, an active flavonoid from the root of Glycyrrhiza glabra

Cao, Jie, Chen, Xiao, Liang, Jun, Yu, Xue-Qing, Xu, An-Long, Chan, Eli, Duan, Wei, Huang, Min, Wen, Jing-Yuan, Yu, Xi-Yong, Li, Xiao-Tian, Sheu, Fwu-Shan and Zhou, Shu-Feng 2007, Role of P-glycoprotein in the intestinal absorption of glabridin, an active flavonoid from the root of Glycyrrhiza glabra, Drug metabolism and disposition, vol. 35, no. 4, pp. 539-553, doi: 10.1124/dmd.106.010801.

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Title Role of P-glycoprotein in the intestinal absorption of glabridin, an active flavonoid from the root of Glycyrrhiza glabra
Formatted title Role of P-glycoprotein in the intestinal absorption of glabridin, an active flavonoid from the root of Glycyrrhiza glabra
Author(s) Cao, Jie
Chen, Xiao
Liang, Jun
Yu, Xue-Qing
Xu, An-Long
Chan, Eli
Duan, WeiORCID iD for Duan, Wei orcid.org/0000-0001-5782-9184
Huang, Min
Wen, Jing-Yuan
Yu, Xi-Yong
Li, Xiao-Tian
Sheu, Fwu-Shan
Zhou, Shu-Feng
Journal name Drug metabolism and disposition
Volume number 35
Issue number 4
Start page 539
End page 553
Total pages 15
Publisher American Society for Pharmacology and Experimental Therapeutics
Place of publication Bethesda, Md.
Publication date 2007-04
ISSN 0090-9556
1521-009X
Keyword(s) ATP-Binding Cassette Transporters
Administration, Oral
Animals
Biological Availability
Biological Transport, Active
Caco-2 Cells
Cell Membrane Permeability
Digoxin
Dose-Response Relationship, Drug
Drugs, Chinese Herbal
Flavonoids
Glucuronides
Glycyrrhiza
Humans
In Vitro Techniques
Intestinal Absorption
Intestines
Isoflavones
Mice
Mice, Knockout
Microsomes, Liver
Models, Biological
Molecular Structure
P-Glycoprotein
P-Glycoproteins
Phenols
Plant Roots
Rats
Rats, Sprague-Dawley
Time Factors
Transfection
Uridine Diphosphate Glucuronic Acid
Verapamil
Language eng
DOI 10.1124/dmd.106.010801
Field of Research 1115 Pharmacology And Pharmaceutical Sciences
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©2007, ASPET
Persistent URL http://hdl.handle.net/10536/DRO/DU:30099149

Document type: Journal Article
Collection: School of Medicine
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