Facile control over the supramolecular ordering of self-assembled peptide scaffolds by simultaneous assembly with a polysacharride Li, Rui, Boyd-Moss, Mitchell, Long, Benjamin, Martel, Anne, Parnell, Andrew, Dennison, Andrew J. C., Barrow, Colin J., Nisbet, David R. and Williams, Richard J. 2017, Facile control over the supramolecular ordering of self-assembled peptide scaffolds by simultaneous assembly with a polysacharride, Scientific reports, vol. 7, no. 1, pp. 1-8, doi: 10.1038/s41598-017-04643-3. Attached Files Name Description MIMEType Size Downloads li-facilecontrol-2017.pdf Published version application/pdf 1.65MB 115 Title Facile control over the supramolecular ordering of self-assembled peptide scaffolds by simultaneous assembly with a polysacharride Author(s) Li, Rui Boyd-Moss, Mitchell Long, Benjamin Martel, Anne Parnell, Andrew Dennison, Andrew J. C. Barrow, Colin J. orcid.org/0000-0002-2153-7267 Nisbet, David R. Williams, Richard J. Journal name Scientific reports Volume number 7 Issue number 1 Article ID 4797 Start page 1 End page 8 Total pages 8 Publisher Nature Publishing Group Place of publication London, Eng. Publication date 2017-07-06 ISSN 2045-2322 Keyword(s) Science & Technology Multidisciplinary Sciences Science & Technology - Other Topics CONTROLLED-RELEASE SMALL MOLECULES BROWN-ALGAE HYDROGEL FUCOIDAN POLYELECTROLYTE BIOMATERIALS PROTEINS CELLS Summary Enabling control over macromolecular ordering and the spatial distribution of structures formed via the mechanisms of molecular self-assembly is a challenge that could yield a range of new functional materials. In particular, using the self-assembly of minimalist peptides, to drive the incorporation of large complex molecules will allow a functionalization strategy for the next generation of biomaterial engineering. Here, for the first time, we show that co-assembly with increasing concentrations of a highly charged polysaccharide, fucoidan, the microscale ordering of Fmoc-FRGDF peptide fibrils and subsequent mechanical properties of the resultant hydrogel can be easily and effectively manipulated without disruption to the nanofibrillar structure of the assembly. Language eng DOI 10.1038/s41598-017-04643-3 Field of Research 030699 Physical Chemistry not elsewhere classified 030199 Analytical Chemistry not elsewhere classified HERDC Research category C1 Refereed article in a scholarly journal ERA Research output type C Journal article Copyright notice ©2017, The Authors Free to Read? Yes Use Rights Persistent URL http://hdl.handle.net/10536/DRO/DU:30099766 Document type: Journal Article Collections: Faculty of Science, Engineering and Built Environment Open Access Collection Centre for Biotechnology, Chemistry and Systems Biology Related Links Link Description Connect to published version Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au. Versions Version Filter Type Wed, 26 Jul 2017, 12:42:38 EST Thu, 27 Jul 2017, 05:14:04 EST Sat, 12 Aug 2017, 06:08:37 EST Tue, 15 Aug 2017, 11:14:16 EST Tue, 15 Aug 2017, 11:18:10 EST Mon, 21 Aug 2017, 09:43:02 EST Fri, 07 Sep 2018, 12:43:08 EST Filtered Full Citation counts:   Cited 9 times in TR Web of Science Cited 9 times in Scopus Search Google Scholar Access Statistics: 522 Abstract Views, 116 File Downloads  -  Detailed Statistics Created: Wed, 26 Jul 2017, 12:42:38 EST

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