Copper and zinc binding modulates the aggregation and neurotoxic properties of the prion peptide PrP106-126

Jobling, Michael F., Huang, Xudong, Stewart, Leanne R., Barnham, Kevin J., Curtain, Cyril, Volitakis, Irene, Perugini, Matthew, White, Anthony R., Cherny, Robert A., Masters, Colin L., Barrow, Colin J., Collins, Steven J., Bush, Ashley I. and Cappai, Roberto 2001, Copper and zinc binding modulates the aggregation and neurotoxic properties of the prion peptide PrP106-126, Biochemistry, vol. 40, no. 27, pp. 8073-8084, doi: 10.1021/bi0029088.


Title Copper and zinc binding modulates the aggregation and neurotoxic properties of the prion peptide PrP106-126
Author(s) Jobling, Michael F.
Huang, Xudong
Stewart, Leanne R.
Barnham, Kevin J.
Curtain, Cyril
Volitakis, Irene
Perugini, Matthew
White, Anthony R.
Cherny, Robert A.
Masters, Colin L.
Barrow, Colin J.ORCID iD for Barrow, Colin J. orcid.org/0000-0002-2153-7267
Collins, Steven J.
Bush, Ashley I.
Cappai, Roberto
Journal name Biochemistry
Volume number 40
Issue number 27
Start page 8073
End page 8084
Total pages 12
Publisher American Chemical Society
Place of publication Washington, D.C.
Publication date 2001-07-10
ISSN 0006-2960
Keyword(s) Amino Acid Sequence
Animals
Binding Sites
Cation Exchange Resins
Cells, Cultured
Cerebellum
Chelating Agents
Chromatography, High Pressure Liquid
Circular Dichroism
Copper
Electron Spin Resonance Spectroscopy
Histidine
Humans
Mass Spectrometry
Methionine
Mice
Mice, Knockout
Molecular Sequence Data
Mutagenesis, Site-Directed
Nephelometry and Turbidimetry
Neurons
Nuclear Magnetic Resonance, Biomolecular
Peptide Fragments
Prions
Protein Structure, Secondary
Resins, Synthetic
Ultracentrifugation
Zinc
Language eng
DOI 10.1021/bi0029088
Field of Research 0601 Biochemistry And Cell Biology
1101 Medical Biochemistry And Metabolomics
0304 Medicinal And Biomolecular Chemistry
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©2001, American Chemical Society
Persistent URL http://hdl.handle.net/10536/DRO/DU:30099778

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