The hydrophobic core sequence modulates the neurotoxic and secondary structure properties of the prion peptide 106-126

Jobling, Michael F., Stewart, Leanne R., White, Anthony R., McLean, Catriona, Friedhuber, Anna, Maher, Fran, Beyreuther, Konrad, Masters, Colin L., Barrow, Colin J., Collins, Steven J. and Cappai, Roberto 1999, The hydrophobic core sequence modulates the neurotoxic and secondary structure properties of the prion peptide 106-126, Journal of neurochemistry, vol. 73, no. 4, pp. 1557-1565, doi: 10.1046/j.1471-4159.1999.0731557.x.

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Title The hydrophobic core sequence modulates the neurotoxic and secondary structure properties of the prion peptide 106-126
Author(s) Jobling, Michael F.
Stewart, Leanne R.
White, Anthony R.
McLean, Catriona
Friedhuber, Anna
Maher, Fran
Beyreuther, Konrad
Masters, Colin L.
Barrow, Colin J.ORCID iD for Barrow, Colin J. orcid.org/0000-0002-2153-7267
Collins, Steven J.
Cappai, Roberto
Journal name Journal of neurochemistry
Volume number 73
Issue number 4
Start page 1557
End page 1565
Total pages 9
Publisher Lippincott Williams & Wilkins
Place of publication Philadelphia, Pa.
Publication date 1999-10
ISSN 0022-3042
1471-4159
Keyword(s) neurotoxicity
turbidometry
peptide aggregation
fibrillogenesis
β-sheet conformation
amyloid
Creutzfeldt-Jakob disease
Alanine
Amino Acid Sequence
Amino Acid Substitution
Animals
Cell Survival
Cells, Cultured
Cerebellum
Circular Dichroism
Humans
Mice
Mice, Inbred C57BL
Mice, Inbred Strains
Mice, Knockout
Molecular Sequence Data
Nephelometry and Turbidimetry
Neurons
Neurotoxins
Peptide Fragments
Peptides
Prions
Protein Structure, Secondary
Sequence Deletion
Structure-Activity Relationship
Language eng
DOI 10.1046/j.1471-4159.1999.0731557.x
Field of Research 1109 Neurosciences
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©1999, International Society for Neurochemistry
Persistent URL http://hdl.handle.net/10536/DRO/DU:30099794

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