Structure determination, pharmacological evaluation, and structure-activity studies of a new cyclic peptide substance P antagonist containing the new amino acid 3-prenyl-beta-hydroxytyrosine, isolated from Aspergillus flavipes

Barrow, Colin J, Doleman, Muriel S, Bobko, Mark A and Cooper, Raymond 1994, Structure determination, pharmacological evaluation, and structure-activity studies of a new cyclic peptide substance P antagonist containing the new amino acid 3-prenyl-beta-hydroxytyrosine, isolated from Aspergillus flavipes, Journal of medicinal chemistry, vol. 37, no. 3, pp. 356-363, doi: 10.1021/jm00029a007.

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Title Structure determination, pharmacological evaluation, and structure-activity studies of a new cyclic peptide substance P antagonist containing the new amino acid 3-prenyl-beta-hydroxytyrosine, isolated from Aspergillus flavipes
Author(s) Barrow, Colin JORCID iD for Barrow, Colin J orcid.org/0000-0002-2153-7267
Doleman, Muriel S
Bobko, Mark A
Cooper, Raymond
Journal name Journal of medicinal chemistry
Volume number 37
Issue number 3
Start page 356
End page 363
Total pages 8
Publisher American Chemical Society
Place of publication Washington, D.C.
Publication date 1994-02-01
ISSN 0022-2623
Keyword(s) amino acid sequence
animals
aspergillus
binding, competitive
dihydroxyphenylalanine
guinea pigs
humans
ileum
molecular sequence data
molecular structure
muscle contraction
peptides, cyclic
receptors, neurokinin-1
structure-activity relationship
substance P
Language eng
DOI 10.1021/jm00029a007
Field of Research 0304 Medicinal And Biomolecular Chemistry
1115 Pharmacology And Pharmaceutical Sciences
0305 Organic Chemistry
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©1994, American Chemical Society
Persistent URL http://hdl.handle.net/10536/DRO/DU:30099808

Document type: Journal Article
Collection: School of Life and Environmental Sciences
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