Synthesis and evaluation of human phosphodiesterases (PDE) 5 inhibitor analogs as trypanosomal PDE inhibitors. Part 1. Sildenafil analogs

Wang, Cuihua, Ashton, Trent D, Gustafson, Alden, Bland, Nicholas D, Ochiana, Stefan O, Campbell, Robert K and Pollastri, Michael P 2012, Synthesis and evaluation of human phosphodiesterases (PDE) 5 inhibitor analogs as trypanosomal PDE inhibitors. Part 1. Sildenafil analogs, Bioorganic & medicinal chemistry letters, vol. 22, no. 7, pp. 2579-2581, doi: 10.1016/j.bmcl.2012.01.119.

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Title Synthesis and evaluation of human phosphodiesterases (PDE) 5 inhibitor analogs as trypanosomal PDE inhibitors. Part 1. Sildenafil analogs
Author(s) Wang, Cuihua
Ashton, Trent DORCID iD for Ashton, Trent D orcid.org/0000-0002-6707-6064
Gustafson, Alden
Bland, Nicholas D
Ochiana, Stefan O
Campbell, Robert K
Pollastri, Michael P
Journal name Bioorganic & medicinal chemistry letters
Volume number 22
Issue number 7
Start page 2579
End page 2581
Total pages 3
Publisher Elsevier
Place of publication Amsterdam, The Netherlands
Publication date 2012-04-01
ISSN 0960-894X
1464-3405
Keyword(s) Animals
Biological Assay
Humans
Phosphodiesterase 5 Inhibitors
Phosphoric Diester Hydrolases
Piperazines
Protozoan Proteins
Purines
Sildenafil Citrate
Solutions
Structure-Activity Relationship
Sulfones
Trypanocidal Agents
Trypanosoma brucei brucei
Language eng
DOI 10.1016/j.bmcl.2012.01.119
Field of Research 0304 Medicinal And Biomolecular Chemistry
1115 Pharmacology And Pharmaceutical Sciences
0305 Organic Chemistry
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©2012, Elsevier Ltd.
Persistent URL http://hdl.handle.net/10536/DRO/DU:30101777

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