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Risk factors and in-hospital outcome of acute ST segment elevation myocardial infarction in young Bangladeshi adults

Karim, Mohammad Azizul, Majumder, Abdullah Al Shafi, Islam, Khandaker Qamrul, Alam, Muhammad Badrul, Paul, Makhan Lal, Islam, Mohammad Shafiqul, Chowdhury, Kamrun N. and Islam, Sheihk Mohammed Shariful 2015, Risk factors and in-hospital outcome of acute ST segment elevation myocardial infarction in young Bangladeshi adults, BMC cardiovascular disorders, vol. 15, pp. 1-8, doi: 10.1186/s12872-015-0069-2.

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Title Risk factors and in-hospital outcome of acute ST segment elevation myocardial infarction in young Bangladeshi adults
Author(s) Karim, Mohammad Azizul
Majumder, Abdullah Al Shafi
Islam, Khandaker Qamrul
Alam, Muhammad Badrul
Paul, Makhan Lal
Islam, Mohammad Shafiqul
Chowdhury, Kamrun N.
Islam, Sheihk Mohammed SharifulORCID iD for Islam, Sheihk Mohammed Shariful orcid.org/0000-0001-7926-9368
Journal name BMC cardiovascular disorders
Volume number 15
Article ID 73
Start page 1
End page 8
Total pages 8
Publisher BioMed Central
Place of publication London, Eng.
Publication date 2015-07-22
ISSN 1471-2261
Keyword(s) Adult
Age Factors
Aged
Bangladesh
Electrocardiography
Feeding Behavior
Female
Hospital Mortality
Humans
Length of Stay
Male
Middle Aged
Myocardial Infarction
Prognosis
Prospective Studies
Risk Factors
Ultrasonography
Summary Background
South Asians have a higher overall incidence rate and younger age of onset for acute myocardial infarction (AMI) compared to Western populations. However, limited information is available on the association of preventable risk factors and outcomes of AMI among young individuals in Bangladesh. The aim of this study was to determine the risk factors and in-hospital outcome of AMI among young (age ≤40 years) adults in Bangladesh.

Methods
We conducted a prospective observational study among consecutive 50 patients aged ≤40 years and 50 patients aged >40 years with acute ST Segment Elevation Myocardial Infarction (STEMI) and followed-up in-hospital at the National Institute of Cardiovascular Diseases (NICVD). Clinical characteristics, biochemical findings, diet, echocardiography and in-hospital outcomes were compared between the two groups. Multivariate logistic regression was performed to assess the association between risk factors and in-hospital outcome in young patients adjusting for other confounding variables.

Results
The mean age of the young and older patient groups was 36.5 ± 4.6 years and 57.0 ± 9.1 years respectively. Male sex (OR 3.4, 95 % CI 1.2 − 9.75), smoking (OR 2.4, 95 % CI 1.04 − 5,62), family history of MI (OR 2.4, 95 % CI 1.11 − 5,54), homocysteine (OR 1.2, 95 % CI 1.08 − 1.36), eating rice ≥2 times daily (OR 3.5, 95 % CI 1.15 − 10.6) and eating beef (OR 4.5, 95 % CI 1.83 − 11.3) were significantly associated with the risk of AMI in the young group compared to older group. In multivariate analysis, older patients had significantly greater chance of developing heart failure (OR 7.5, 95 % CI 1.51 to 37.31), re-infarction (OR 7.0, 95 % CI 1.08 − 45.72), arrhythmia (OR 15.3, 95 % CI 2.69 − 87.77) and cardiogenic shock (OR 69.0, 95 % CI 5.81 − 85.52) than the younger group.

Conclusion
Younger AMI patients have a different risk profile and better in-hospital outcomes compared to the older patients. Control of preventable risk factors such as smoking, unhealthy diet, obesity and dyslipidemia should be reinforced at an early age in Bangladesh.
Language eng
DOI 10.1186/s12872-015-0069-2
Field of Research 1102 Cardiovascular Medicine And Haematology
HERDC Research category C1.1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2015, The Authors
Free to Read? Yes
Use Rights Creative Commons Attribution licence
Persistent URL http://hdl.handle.net/10536/DRO/DU:30102369

Document type: Journal Article
Collections: School of Exercise and Nutrition Sciences
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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.