Openly accessible

Mutation profiling of colorectal cancer for KRAS, BRAF, NRAS and PIK3CA genes in Indian patient cohort

Patil, Anant Harshali 2017, Mutation profiling of colorectal cancer for KRAS, BRAF, NRAS and PIK3CA genes in Indian patient cohort, PhD thesis, School of Life and Environmental Sciences, Deakin University.

Attached Files
Name Description MIMEType Size Downloads
patil-mutation-2017.pdf Connect to thesis application/pdf 8.76MB 132

Title Mutation profiling of colorectal cancer for KRAS, BRAF, NRAS and PIK3CA genes in Indian patient cohort
Author Patil, Anant Harshali
Institution Deakin University
School School of Life and Environmental Sciences
Faculty Faculty of Science Engineering and Built Environment
Degree type Research doctorate
Degree name PhD
Thesis advisor Barrow, Colin J.ORCID iD for Barrow, Colin J. orcid.org/0000-0002-2153-7267
Kanwar, Rupinder
Date submitted 2017-01
Keyword(s) molecular biology
colorectal cancer
cancer genes
Indians
biomarkers
medical genetics
Summary  This study investigated the molecular mechanisms that could predict the efficacy of Epidermal Growth Factor Receptor (EGFR) targeted therapy in Indian colorectal cancer (CRC) patients. KRAS, BRAF, NRAS and PIK3CA mutations was studied in 203 Indian CRC patients and mutation analyses of the biomarkers were correlated with clinicopathological findings.
Language eng
Field of Research 111203 Cancer Genetics
111202 Cancer Diagnosis
Socio Economic Objective 920102 Cancer and Related Disorders
Description of original xxix, 297 pages
Copyright notice ┬ęThe Author. All Rights Reserved.
Free to Read? Yes
Persistent URL http://hdl.handle.net/10536/DRO/DU:30103030

Document type: Thesis
Collections: Higher degree theses (Open Access)
Open Access Collection
Connect to link resolver
 
Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved.

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.

Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 0 times in TR Web of Science
Scopus Citation Count Cited 0 times in Scopus
Google Scholar Search Google Scholar
Access Statistics: 88 Abstract Views, 133 File Downloads  -  Detailed Statistics
Created: Fri, 06 Oct 2017, 07:58:02 EST by Asif, Yasmin

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.