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No protein intake compensation for insufficient indispensable amino acid intake with a low-protein diet for 12 days

Martens, Eveline A, Tan, Sze Yen, Mattes, Richard D and Westerterp-Plantenga, Margriet S 2014, No protein intake compensation for insufficient indispensable amino acid intake with a low-protein diet for 12 days, Nutrition and metabolism, vol. 11, pp. 1-8, doi: 10.1186/1743-7075-11-38.

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Title No protein intake compensation for insufficient indispensable amino acid intake with a low-protein diet for 12 days
Author(s) Martens, Eveline A
Tan, Sze Yen
Mattes, Richard D
Westerterp-Plantenga, Margriet S
Journal name Nutrition and metabolism
Volume number 11
Article ID 38
Start page 1
End page 8
Total pages 8
Publisher BioMed Central
Place of publication London, Eng.
Publication date 2014-08-20
ISSN 1743-7075
Keyword(s) DIAAS
iIndispensable amino acids
nitrogen balance
protein intake
protein source
science & technology
life sciences & biomedicine
nutrition & dietetics
Summary Background
Protein quality evaluation aims to determine the capacity of food sources and diets to meet protein and indispensable amino acid (IAA) requirements. This study determined whether nitrogen balance was affected and whether dietary IAA were adequately obtained from the ad libitum consumption of diets at three levels of protein from different primary sources for 12 days.

Methods
Two 12-day randomized crossover design trials were conducted in healthy subjects [n = 70/67 (M/F); age: 19-70 y; BMI: 18.2-38.7 kg/m2]. The relative dietary protein content was lower than [5% of energy (En%)], similar to (15En%), and higher than (30En%) customary diets. These diets had a limited variety of protein sources, containing wheat protein as a single protein source (5En%-protein diet) or 5En% from wheat protein with 10En% (15En%-protein diets) or 25En% (30En%-protein diets) added from whey with α-lactalbumin, soy or beef protein.

Results

There was a dose-dependent increase in nitrogen excretion with increasing dietary protein content, irrespective of the protein sources (P = 0.001). Nitrogen balance was maintained on the 5En%-protein diet, and was positive on the 15En%- and 30En%-protein diets (P < 0.001) over 12 days. Protein intake from the 5En%-protein diet did not reach the amount necessary to meet the calculated minimal IAA requirements, but IAA were sufficiently obtained from the 15En%- and 30En%-protein diets. In the 15En%- and 30En%-protein conditions, a higher protein intake from the soy-containing diets than from the whey with α-lactalbumin or beef containing diets was needed to meet the minimal IAA requirements.

Conclusion

Protein intake did not compensate for an insufficient indispensable amino acid intake with a low-protein diet for 12 days.
Language eng
DOI 10.1186/1743-7075-11-38
Field of Research 111199 Nutrition and Dietetics not elsewhere classified
0606 Physiology
1106 Human Movement And Sports Science
1111 Nutrition And Dietetics
HERDC Research category C1.1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2014, Martens et al
Free to Read? Yes
Use Rights Creative Commons Attribution licence
Persistent URL http://hdl.handle.net/10536/DRO/DU:30105339

Document type: Journal Article
Collections: School of Exercise and Nutrition Sciences
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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.