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Repurposing auranofin to treat Clostridium difficile infection by targeting selenium

Roder, Christine 2017, Repurposing auranofin to treat Clostridium difficile infection by targeting selenium, Ph.D thesis, School of Medicine, Deakin Univeristy.

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Title Repurposing auranofin to treat Clostridium difficile infection by targeting selenium
Author Roder, Christine
Institution Deakin Univeristy
School School of Medicine
Faculty Faculty of Health
Degree type Research doctorate
Degree name Ph.D
Thesis advisor Athan, EugeneORCID iD for Athan, Eugene orcid.org/0000-0001-9838-6471
Date submitted 2017-11-28
Summary This research investigated the role of selenoproteins in the bacterial human pathogen Clostridium difficile and tested auranofin as a treatment for this infection. Auranofin was found to effectively kill the bacteria and reduce the cytotoxic effect of its toxins, supporting its use as a new treatment for Clostridium difficile infection.
Language eng
Field of Research 110801 Medical Bacteriology
Socio Economic Objective 920109 Infectious Diseases
Copyright notice ┬ęThe author
Free to Read? Yes
Persistent URL http://hdl.handle.net/10536/DRO/DU:30105469

Document type: Thesis
Collections: Higher degree theses (Open Access)
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Created: Thu, 14 Dec 2017, 13:06:26 EST by Asif, Yasmin

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.