Openly accessible

Association between vitamin D insufficiency and metabolic syndrome in patients with psychotic disorders

Yoo, Taeyoung, Choi, Wonsuk, Hong, Jin-Hee, Lee, Ju-Yeon, Kim, Jae-Min, Shin, Il-Seon, Yang, Soo Jin, Amminger, Paul, Berk, Michael, Yoon, Jin-Sang and Kim, Sung-Wan 2018, Association between vitamin D insufficiency and metabolic syndrome in patients with psychotic disorders, Psychiatry investigation, vol. 15, no. 4, pp. 396-401, doi: 10.30773/pi.2017.08.30.

Attached Files
Name Description MIMEType Size Downloads
berk-associationbetween-2018.pdf Published version application/pdf 529.61KB 8

Title Association between vitamin D insufficiency and metabolic syndrome in patients with psychotic disorders
Author(s) Yoo, Taeyoung
Choi, Wonsuk
Hong, Jin-Hee
Lee, Ju-Yeon
Kim, Jae-Min
Shin, Il-Seon
Yang, Soo Jin
Amminger, Paul
Berk, MichaelORCID iD for Berk, Michael orcid.org/0000-0002-5554-6946
Yoon, Jin-Sang
Kim, Sung-Wan
Journal name Psychiatry investigation
Volume number 15
Issue number 4
Start page 396
End page 401
Total pages 6
Publisher Korean Neuropsychiatric Association
Place of publication Soeul, South Korea
Publication date 2018
ISSN 1738-3684
Keyword(s) Hypertension
Metabolic syndrome
Psychotic disorder
Schizophrenia
Vitamin D
Science & Technology
Life Sciences & Biomedicine
Psychiatry
NUTRITION EXAMINATION SURVEY
RANDOMIZED CONTROLLED-TRIAL
KOREAN NATIONAL-HEALTH
D DEFICIENCY
CARDIOVASCULAR-DISEASE
INSULIN-RESISTANCE
RISK-FACTORS
POPULATION
PREVALENCE
Summary Objective
This study examined the association between vitamin D and metabolic syndrome in patients with psychotic disorders.

Methods
The study enrolled 302 community-dwelling patients with psychotic disorders. Sociodemographic and clinical characteristics, including blood pressure, physical activity, and dietary habit were gathered. Laboratory examinations included vitamin D, lipid profile, fasting plasma glucose, HbA1c, liver function, and renal function. Vitamin D insufficiency was defined as <20 ng/mL. Clinical characteristics associated with vitamin D insufficiency were identified.

Results
Among the 302 participants, 236 patients (78.1%) had a vitamin D insufficiency and 97 (32.1%) had metabolic syndrome. Vitamin D insufficiency was significantly associated with the presence of metabolic syndrome (p=0.006) and hypertension (p=0.017). Significant increases in triglycerides and alanine transaminase were observed in the group with a vitamin D insufficiency (p=0.002 and 0.011, respectively). After adjusting for physical activity and dietary habit scores, vitamin D insufficiency remained significantly associated with metabolic syndrome and hypertension.

Conclusion
Vitamin D insufficiency was associated with metabolic syndrome and was particularly associated with high blood pressure, although the nature, direction and implications of this association are unclear.
Language eng
DOI 10.30773/pi.2017.08.30
Field of Research 110999 Neurosciences not elsewhere classified
Socio Economic Objective 920410 Mental Health
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2018, Korean Neuropsychiatric Association
Free to Read? Yes
Use Rights Creative Commons Attribution non-commercial licence
Persistent URL http://hdl.handle.net/10536/DRO/DU:30108883

Document type: Journal Article
Collections: School of Medicine
Open Access Collection
Connect to link resolver
 
Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved.

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.

Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 0 times in TR Web of Science
Scopus Citation Count Cited 2 times in Scopus
Google Scholar Search Google Scholar
Access Statistics: 34 Abstract Views, 9 File Downloads  -  Detailed Statistics
Created: Thu, 31 May 2018, 19:36:43 EST

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.