Development of a novel CD4+ TCR transgenic line that reveals a dominant role for CD8+ dendritic cells and CD40 signaling in the generation of helper and CTL responses to blood-stage malaria

Fernandez-Ruiz, Daniel, Lau, Lei Shong, Ghazanfari, Nazanin, Jones, Claerwen M, Ng, Wei Yi, Davey, Gayle M, Berthold, Dorothee, Holz, Lauren, Kato, Yu, Enders, Matthias H, Bayarsaikhan, Ganchimeg, Hendriks, Sanne H, Lansink, Lianne IM, Engel, Jessica A, Soon, Megan SF, James, Kylie R, Cozijnsen, Anton, Mollard, Vanessa, Uboldi, Alessandro D, Tonkin, Christopher J, De Koning-Ward, Tania, Gilson, Paul R, Kaisho, Tsuneyasu, Haque, Ashraful, Crabb, Brendan S, Carbone, Francis R, McFadden, Geoffrey I and Heath, William R 2017, Development of a novel CD4+ TCR transgenic line that reveals a dominant role for CD8+ dendritic cells and CD40 signaling in the generation of helper and CTL responses to blood-stage malaria, Journal of immunology, vol. 199, no. 12, pp. 4165-4179, doi: 10.4049/jimmunol.1700186.

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Title Development of a novel CD4+ TCR transgenic line that reveals a dominant role for CD8+ dendritic cells and CD40 signaling in the generation of helper and CTL responses to blood-stage malaria
Author(s) Fernandez-Ruiz, Daniel
Lau, Lei Shong
Ghazanfari, Nazanin
Jones, Claerwen M
Ng, Wei Yi
Davey, Gayle M
Berthold, Dorothee
Holz, Lauren
Kato, Yu
Enders, Matthias H
Bayarsaikhan, Ganchimeg
Hendriks, Sanne H
Lansink, Lianne IM
Engel, Jessica A
Soon, Megan SF
James, Kylie R
Cozijnsen, Anton
Mollard, Vanessa
Uboldi, Alessandro D
Tonkin, Christopher J
De Koning-Ward, TaniaORCID iD for De Koning-Ward, Tania orcid.org/0000-0001-5810-8063
Gilson, Paul R
Kaisho, Tsuneyasu
Haque, Ashraful
Crabb, Brendan S
Carbone, Francis R
McFadden, Geoffrey I
Heath, William R
Journal name Journal of immunology
Volume number 199
Issue number 12
Start page 4165
End page 4179
Total pages 15
Publisher American Association of Immunologists
Place of publication Bethesda, Md.
Publication date 2017-12-15
ISSN 0022-1767
1550-6606
Keyword(s) animals
antigen presentation
antigens, protozoan
CD4-positive T-lymphocytes
CD40 antigens
CD40 ligand
cells, cultured
crosses, genetic
dendritic cells
hybridomas
lymphocyte activation
malaria
malaria, cerebral
mice, inbred BALB C
mice, inbred C57BL
mice, transgenic
parasitemia
plasmodium berghei
radiation chimera
T-lymphocytes, cytotoxic
science & technology
life sciences & biomedicine
immunology
Language eng
DOI 10.4049/jimmunol.1700186
Field of Research 1107 Immunology
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2017, The American Association of Immunologists, Inc.
Persistent URL http://hdl.handle.net/10536/DRO/DU:30109421

Document type: Journal Article
Collection: School of Medicine
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