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You can't fix what isn't broken: Eight weeks of exercise do not substantially change cognitive function and biochemical markers in young and healthy adults

Gourgouvelis, Joanne, Yielder, Paul, Clarke, Sandra T., Behbahani, Hushyar and Murphy, Bernadette 2018, You can't fix what isn't broken: Eight weeks of exercise do not substantially change cognitive function and biochemical markers in young and healthy adults, PeerJ, pp. 1-16, doi: 10.7717/peerj.4675.

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Title You can't fix what isn't broken: Eight weeks of exercise do not substantially change cognitive function and biochemical markers in young and healthy adults
Author(s) Gourgouvelis, Joanne
Yielder, Paul
Clarke, Sandra T.
Behbahani, Hushyar
Murphy, Bernadette
Journal name PeerJ
Article ID e4675
Start page 1
End page 16
Total pages 16
Publisher PeerJ Inc
Place of publication Corte Madera, Calif.
Publication date 2018-01-01
ISSN 2167-8359
Keyword(s) Exercise
BDNF
Cathepsin B
Cognitive function
Summary Objective
The benefits of exercise on brain health is well known in aging and psychiatric populations. However, the relationship between habitual exercise in young and healthy adults remains unclear. This study explored the effects an eight-week exercise prescription on cognitive function, brain-derived neurotrophic factor (BDNF) and cathepsin B (CTHB) in young and healthy adults.

Methods
A total of 22 low-active, young and healthy adults were recruited from a local university. A total of 12 participants performed an eight-week exercise prescription and 12 participants served as controls. Cognitive assessments, cardiorespiratory fitness and plasma BDNF and CTHB concentrations were measured at baseline and eight weeks.

Results
Results showed exercise improved cardiorespiratory fitness (p = 0.044, d = 1.48) with no improvements in cognitive function or no changes in plasma BDNF and CTHB concentrations.

Conclusion

We provide evidence that a short-term course of moderate exercise does not improve cognitive function or change plasma biochemical markers concentrations in young and healthy adults, despite mild improvements in cardiorespiratory fitness. These results suggest that cognitive health may peak during early adulthood leaving little room for improvement throughout this period of the lifespan.
Language eng
DOI 10.7717/peerj.4675
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2018, The Authors
Free to Read? Yes
Use Rights Creative Commons Attribution licence
Persistent URL http://hdl.handle.net/10536/DRO/DU:30110536

Document type: Journal Article
Collections: School of Medicine
Open Access Collection
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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.