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Psychopathological features of bipolar depression: Italian validation of the Bipolar Depression Rating Scale (I-BDRS).

Bruschi, Angelo, Mazza, Marianna, Camardese, Giovanni, Calò, Salvatore, Palumbo, Claudia, Mandelli, Laura, Callea, Antonino, Gori, Alessio, Di Nicola, Marco, Marano, Giuseppe, Berk, Michael, di Sciascio, Guido and Janiri, Luigi 2018, Psychopathological features of bipolar depression: Italian validation of the Bipolar Depression Rating Scale (I-BDRS)., Frontiers in psychology, vol. 9, doi: 10.3389/fpsyg.2018.01047.

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Title Psychopathological features of bipolar depression: Italian validation of the Bipolar Depression Rating Scale (I-BDRS).
Author(s) Bruschi, Angelo
Mazza, Marianna
Camardese, Giovanni
Calò, Salvatore
Palumbo, Claudia
Mandelli, Laura
Callea, Antonino
Gori, Alessio
Di Nicola, Marco
Marano, Giuseppe
Berk, MichaelORCID iD for Berk, Michael orcid.org/0000-0002-5554-6946
di Sciascio, Guido
Janiri, Luigi
Journal name Frontiers in psychology
Volume number 9
Article ID 1047
Publisher Frontiers
Place of publication Lausanne, Switzerland
Publication date 2018-06
ISSN 1664-1078
Keyword(s) bipolar depression rating scale
bipolar disorder
depression
mania
mixed state
unipolar
validation
Social Sciences
Psychology, Multidisciplinary
Psychology
WEEKLY SYMPTOMATIC STATUS
1-YEAR FOLLOW-UP
NATURAL-HISTORY
MANIC SYMPTOMS
MIXED-STATE
STEP-BD
UNIPOLAR DEPRESSION
CLINICAL-FEATURES
DISORDER
EPIDEMIOLOGY
Summary Background: Aim of the study was the validation of the Bipolar Disorder Rating Scale (BDRS) in an Italian population. Secondary aim was the evaluation of differences between unipolar and bipolar depression and between bipolar I and II depressed patients.

Method: 125 Bipolar Disorder and 60 Major Depressive Disorder patients were administered an Italian translation of the BDRS (I-BDRS), Hamilton Depression Rating Scale (HDRS), Montgomery-Asberg Depression Rating Scale (MADRS), Young Mania Rating Scale (YMRS) and Temperament and Character Inventory-Revised (TCI-R). 
Results: I-BDRS showed considerable validity and reliability. Factor analysis found 3 subscales, two linked to depressive symptoms and one to mixed symptoms. Measures concerning depression (MADRS and HAM-D) were positively related to the I-BDRS's subscales, but mostly to the two subscales measuring depression. In mixed symptoms, the mean of the bipolar group was significantly higher than the unipolar group suggesting that the BDRS was able to distinguish between unipolar and bipolar depressed patients.

Conclusion: I-BDRS is a valid scale for the measurement of depression in BD patients, with a notable internal consistency (Cronbach's α 0.82), a significant consistency between items/total (Cronbach's α from 0.80 to 0.82) and positive correlation with other scales (MADRS r = 0.67, p < 0.001; HDRS r = 0.81, p < 0.001; YMRS r = 0.46 p < 0.0001). The mixed state sub-scale shows usefulness in differentiating bipolar from unipolar patients. I-BDRS could be a sensitive tool, both in pure depression and in mixed states, and could be used in the everyday screening and treatment of Bipolar Disorder.
Language eng
DOI 10.3389/fpsyg.2018.01047
Field of Research 1701 Psychology
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2018, Bruschi, Mazza, Camardese, Calò, Palumbo, Mandelli, Callea, Gori, Di Nicola, Marano, Berk, di Sciascio and Janiri.
Free to Read? Yes
Use Rights Creative Commons Attribution licence
Persistent URL http://hdl.handle.net/10536/DRO/DU:30111758

Document type: Journal Article
Collections: School of Medicine
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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.