The MUC1 mucin protects against Helicobacter pylori pathogenesis in mice by regulation of the NLRP3 inflammasome

Ng, Garrett Z., Menheniott, Trevekyan R., Every, Alison L., Stent, Andrew, Judd, Louise M., Chionh, Yok Teng, Dhar, Poshmaal, Komen, Jasper C., Giraud, Andrew S., Wang, Timothy C., McGuckin, Michael A. and Sutton, Philip 2016, The MUC1 mucin protects against Helicobacter pylori pathogenesis in mice by regulation of the NLRP3 inflammasome, Gut, vol. 65, no. 7, pp. 1087-1099, doi: 10.1136/gutjnl-2014-307175.

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Title The MUC1 mucin protects against Helicobacter pylori pathogenesis in mice by regulation of the NLRP3 inflammasome
Formatted title  The MUC1 mucin protects against Helicobacter pylori pathogenesis in mice by regulation of the NLRP3 inflammasome
Author(s) Ng, Garrett Z.
Menheniott, Trevekyan R.
Every, Alison L.
Stent, Andrew
Judd, Louise M.
Chionh, Yok Teng
Dhar, PoshmaalORCID iD for Dhar, Poshmaal orcid.org/0000-0002-2842-007X
Komen, Jasper C.
Giraud, Andrew S.
Wang, Timothy C.
McGuckin, Michael A.
Sutton, Philip
Journal name Gut
Volume number 65
Issue number 7
Start page 1087
End page 1099
Total pages 13
Publisher BMJ Publishing Group
Place of publication London, Eng
Publication date 2016-07
ISSN 1468-3288
Keyword(s) GASTRIC CANCER
HELICOBACTER PYLORI - GASTRITIS
INFLAMMATORY MECHANISMS
MUCINS
Animals
Caspase 1
DNA Methylation
Female
Gastric Mucosa
Gastritis
Gene Expression
Helicobacter Infections
Helicobacter pylori
Inflammasomes
Interleukin-1 Receptor-Associated Kinases
Interleukin-1beta
Macrophages
Mice
Mice, Inbred C57BL
Mice, Knockout
Monocytes
Mucin-1
NF-kappa B
NLR Family, Pyrin Domain-Containing 3 Protein
Signal Transduction
Time Factors
Trefoil Factor-2
Science & Technology
Life Sciences & Biomedicine
Gastroenterology & Hepatology
CAG PATHOGENICITY ISLAND
DENDRITIC CELLS
GASTRIC-CANCER
CUTTING EDGE
INTERLEUKIN-1 POLYMORPHISMS
IL-1-BETA PRODUCTION
EXPRESSION
INFECTION
RECEPTOR
SECRETION
Language eng
DOI 10.1136/gutjnl-2014-307175
Field of Research 1103 Clinical Sciences
1114 Paediatrics And Reproductive Medicine
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2016, BMJ
Persistent URL http://hdl.handle.net/10536/DRO/DU:30112695

Document type: Journal Article
Collections: Faculty of Health
School of Medicine
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