Development of novel activin-targeted therapeutics

Chen, Justin L., Walton, Kelly L., Al-Musawi, Sara L., Kelly, Emily K., Qian, Hongwei, La, Mylinh, Lu, Louis, Lovrecz, George, Ziemann, Mark, Lazarus, Ross, El-Osta, Assam, Gregorevic, Paul and Harrison, Craig A. 2015, Development of novel activin-targeted therapeutics, Molecular therapy, vol. 23, no. 3, pp. 434-444, doi: 10.1038/mt.2014.221.

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Title Development of novel activin-targeted therapeutics
Author(s) Chen, Justin L.
Walton, Kelly L.
Al-Musawi, Sara L.
Kelly, Emily K.
Qian, Hongwei
La, Mylinh
Lu, Louis
Lovrecz, George
Ziemann, MarkORCID iD for Ziemann, Mark orcid.org/0000-0002-7688-6974
Lazarus, Ross
El-Osta, Assam
Gregorevic, Paul
Harrison, Craig A.
Journal name Molecular therapy
Volume number 23
Issue number 3
Start page 434
End page 444
Total pages 12
Publisher Elsevier
Place of publication Amsterdam, The Netherlands
Publication date 2015-03
ISSN 1525-0024
Keyword(s) Activins
Animals
Bone Morphogenetic Proteins
Dependovirus
Gene Expression Regulation
Genetic Engineering
Genetic Vectors
Growth Differentiation Factors
HEK293 Cells
Humans
Immunoglobulin Fc Fragments
Immunoglobulin G
Male
Mice
Mice, Inbred C57BL
Muscle, Skeletal
Myostatin
Plasmids
Protein Structure, Tertiary
Recombinant Fusion Proteins
Signal Transduction
Transfection
Transforming Growth Factor beta
Science & Technology
Life Sciences & Biomedicine
Biotechnology & Applied Microbiology
Genetics & Heredity
Medicine, Research & Experimental
Research & Experimental Medicine
MUSCLE GROWTH
II RECEPTORS
TRANSGENIC MICE
ACTIVATION
PROTEIN
FOLLISTATIN
CACHEXIA
INHIBIN
MASS
ERYTHROPOIESIS
Language eng
DOI 10.1038/mt.2014.221
Field of Research 06 Biological Sciences
10 Technology
11 Medical And Health Sciences
HERDC Research category C1.1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2015, The American Society of Gene & Cell Therapy
Persistent URL http://hdl.handle.net/10536/DRO/DU:30112915

Document type: Journal Article
Collection: School of Life and Environmental Sciences
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