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Weight loss surgery for obstructive sleep apnoea with obesity in adults: a systematic review and meta-analysis protocol

Dong, Zhiyong, Hong, Brian Y., Yu, Ashley M., Cathey, John, Islam, Sheikh Mohammed Shariful and Wang, Cunchuan 2018, Weight loss surgery for obstructive sleep apnoea with obesity in adults: a systematic review and meta-analysis protocol, BMJ Open, vol. 8, no. 8, pp. 1-6, doi: 10.1136/bmjopen-2017-020876.

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Title Weight loss surgery for obstructive sleep apnoea with obesity in adults: a systematic review and meta-analysis protocol
Author(s) Dong, Zhiyong
Hong, Brian Y.
Yu, Ashley M.
Cathey, John
Islam, Sheikh Mohammed SharifulORCID iD for Islam, Sheikh Mohammed Shariful orcid.org/0000-0001-7926-9368
Wang, Cunchuan
Journal name BMJ Open
Volume number 8
Issue number 8
Article ID e020876
Start page 1
End page 6
Total pages 6
Publisher BMJ Publishing Group
Place of publication London, Eng.
Publication date 2018-08
ISSN 2044-6055
Keyword(s) bariatric surgery
obesity
obstructive sleep apnoea
weight loss surgery
Summary Introduction Obstructive sleep apnoea (OSA) is causedby complete or partial obstruction of the upper airwayresulting in repeated episodes of interrupted or shallowbreaths. OSA is associated with significant morbidity andmortality. The prevalence is estimated to range from 3%to 7% in the general population but may be much higher.Several studies show that weight loss or bariatric surgerymay have a role in treating OSA. The aim of this systematicreview is to assess the safety and efficacy of randomisedcontrolled trials (RCTs) of weight loss surgery for adultswith OSA and comorbid obesity.Methods and analysis A search of the Cochrane CentralRegister of Controlled Trials, PubMed, EMBASE and twomajor Chinese biomedical databases will be performedto identify related trials published as of October 2018.This study will include RCTs, comparing different typesof weight loss surgery for OSA with obesity or weightloss surgery for OSA with obesity with other upper airwaysurgeries. The primary outcomes that will be measuredare apnoea–hypopnoea index, excess weight loss andin-hospital mortality. The secondary outcomes willinclude duration of hospital stay, neck circumference,reoperation, waist circumference, body mass index,Epworth Sleepiness Scale score, overt complications(eg, gastric fistula, bleeding, delayed gastric emptying,wound infection), quality of life, quality of sleep and/orfunctionality. The systematic review will be conductedaccording to the recommendations as outlined by theCochrane collaboration.Ethics and dissemination The systematic review andmeta-analysis will include published data available onlineand thus ethics approval will not be required. The findingswill be disseminated and published in a peer-reviewedjournal. Review updates will be conducted if there isnew evidence that may cause any change in reviewconclusions. Any changes to the study protocol will beupdated in the PROSPERO trial registry accordingly.
Language eng
DOI 10.1136/bmjopen-2017-020876
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2018, The Authors
Free to Read? Yes
Use Rights Creative Commons Attribution non-commercial licence
Persistent URL http://hdl.handle.net/10536/DRO/DU:30113039

Document type: Journal Article
Collections: School of Exercise and Nutrition Sciences
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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.