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Substance use in adulthood following adolescent self-harm: a population-based cohort study

Moran, P, Coffey, C, Romaniuk, H, Degenhardt, L, Borschmann, R and Patton, GC 2015, Substance use in adulthood following adolescent self-harm: a population-based cohort study, Acta psychiatrica Scandinavica, vol. 131, no. 1, pp. 61-68, doi: 10.1111/acps.12306.

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Title Substance use in adulthood following adolescent self-harm: a population-based cohort study
Author(s) Moran, P
Coffey, C
Romaniuk, H
Degenhardt, L
Borschmann, R
Patton, GC
Journal name Acta psychiatrica Scandinavica
Volume number 131
Issue number 1
Start page 61
End page 68
Total pages 8
Publisher John Wiley & Sons
Place of publication Chichester, Eng.
Publication date 2015-01
ISSN 0001-690X
1600-0447
Keyword(s) self-harm
substance-related disorders
epidemiology
adolescent
adolescent behavior
adulthood
age factors
comorbidity
odds ratio
prospective studies
risk factors
self-injurious behavior
Victoria
science & technology
life sciences & biomedicine
psychiatry
mental health
Summary Objective
To determine whether adolescents who self‐harm are at increased risk of heavy and dependent substance use in adulthood.

Method
Fifteen‐year prospective cohort study of a random sample of 1943 adolescents recruited from secondary schools across the state of Victoria, Australia. Data pertaining to self‐harm and substance use was obtained at seven waves of follow‐up, from mean age 15.9 years to mean age 29.1 years.

Results
Substance use and self‐harm were strongly associated during the adolescent years (odds ratio (OR): 3.3, 95% CI 2.1–5.0). Moreover, adolescent self‐harmers were at increased risk of substance use and dependence syndromes in young adulthood. Self‐harm predicted a four‐fold increase in the odds of multiple dependence syndromes (sex‐ and wave‐adjusted OR: 4.2, 95% CI: 2.7–6.6). Adjustment for adolescent anxiety/depression attenuated but did not eliminate most associations. Adolescent substance use confounded all associations, with the exception of multiple dependence syndromes, which remained robustly associated with adolescent self‐harm (fully adjusted odds ratio: 2.0, 95% CI: 1.2–3.2).

Conclusion
Adolescent self‐harm is an independent risk factor for multiple dependence syndromes in adulthood. This level of substance misuse is likely to contribute substantially to the premature mortality and disease burden experienced by individuals who self‐harm.
Language eng
DOI 10.1111/acps.12306
Field of Research 11 Medical And Health Sciences
17 Psychology And Cognitive Sciences
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2014, The Authors
Free to Read? Yes
Use Rights Creative Commons Attribution Non-Commercial No-Derivatives licence
Persistent URL http://hdl.handle.net/10536/DRO/DU:30113849

Document type: Journal Article
Collections: PVC's Office - Health
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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.