A divergent hepatitis D-like agent in birds

Wille, Michelle, Netter, Hans J., Littlejohn, Margaret, Yuen, Lilly, Shi, Mang, Eden, John-Sebastian, Klaassen, Marcel, Holmes, Edward C. and Hurt, Aeron C. 2018, A divergent hepatitis D-like agent in birds, Viruses, vol. 10, no. 12, doi: 10.3390/v10120720.

Attached Files
Name Description MIMEType Size Downloads

Title A divergent hepatitis D-like agent in birds
Author(s) Wille, Michelle
Netter, Hans J.
Littlejohn, Margaret
Yuen, Lilly
Shi, Mang
Eden, John-Sebastian
Klaassen, MarcelORCID iD for Klaassen, Marcel orcid.org/0000-0003-3907-9599
Holmes, Edward C.
Hurt, Aeron C.
Journal name Viruses
Volume number 10
Issue number 12
Publisher MDPI
Place of publication Basel, Switzerland
Publication date 2018-12-17
ISSN 1999-4915
Keyword(s) co-evolution
dabbling duck
hepatitis D virus
phylogeny
Science & Technology
Life Sciences & Biomedicine
Virology
INTERACTING PROTEIN-A
DELTA-VIRUS
ANTIGEN
ORIGIN
SEQUENCE
REPLICATION
PERFORMANCE
Summary Hepatitis delta virus (HDV) is currently only found in humans and is a satellite virus that depends on hepatitis B virus (HBV) envelope proteins for assembly, release, and entry. Using meta-transcriptomics, we identified the genome of a novel HDV-like agent in ducks. Sequence analysis revealed secondary structures that were shared with HDV, including self-complementarity and ribozyme features. The predicted viral protein shares 32% amino acid similarity to the small delta antigen of HDV and comprises a divergent phylogenetic lineage. The discovery of an avian HDV-like agent has important implications for the understanding of the origins of HDV and sub-viral agents.
Language eng
DOI 10.3390/v10120720
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Grant ID DP160102146
Copyright notice ©2018, The Authors
Persistent URL http://hdl.handle.net/10536/DRO/DU:30117146

Document type: Journal Article
Collections: School of Life and Environmental Sciences
Open Access Checking
Connect to link resolver
 
Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved.

Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 1 times in TR Web of Science
Scopus Citation Count Cited 1 times in Scopus
Google Scholar Search Google Scholar
Access Statistics: 22 Abstract Views, 1 File Downloads  -  Detailed Statistics
Created: Tue, 29 Jan 2019, 09:24:36 EST

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.