Evaluation of 4-amino 2-anilinoquinazolines against Plasmodium and other apicomplexan parasites in vitro and in a P. falciparum humanized NOD-scid IL2Rγnull mouse model of malaria

Gilson, Paul R, Nguyen, William, Poole, William A, Teixeira, Jose E, Thompson, Jennifer K, Guo, Kaiyuan, Stewart, Rebecca J, Ashton, Trent D, White, Karen L, Sanz, Laura M, Gamo, Francisco-Javier, Charman, Susan A, Wittlin, Sergio, Duffy, James, Tonkin, Christopher J, Tham, Wai-Hong, Crabb, Brendan S, Cooke, Brian M, Huston, Christopher D, Cowman, Alan F and Sleebs, Brad E 2019, Evaluation of 4-amino 2-anilinoquinazolines against Plasmodium and other apicomplexan parasites in vitro and in a P. falciparum humanized NOD-scid IL2Rγnull mouse model of malaria, Antimicrobial agents and chemotherapy, vol. 63, pp. e01804-e01818, doi: 10.1128/AAC.01804-18.


Title Evaluation of 4-amino 2-anilinoquinazolines against Plasmodium and other apicomplexan parasites in vitro and in a P. falciparum humanized NOD-scid IL2Rγnull mouse model of malaria
Author(s) Gilson, Paul R
Nguyen, William
Poole, William A
Teixeira, Jose E
Thompson, Jennifer K
Guo, Kaiyuan
Stewart, Rebecca J
Ashton, Trent DORCID iD for Ashton, Trent D orcid.org/0000-0002-6707-6064
White, Karen L
Sanz, Laura M
Gamo, Francisco-Javier
Charman, Susan A
Wittlin, Sergio
Duffy, James
Tonkin, Christopher J
Tham, Wai-Hong
Crabb, Brendan S
Cooke, Brian M
Huston, Christopher D
Cowman, Alan F
Sleebs, Brad E
Journal name Antimicrobial agents and chemotherapy
Volume number 63
Start page e01804
End page e01818
Total pages 15
Publisher American Society for Microbiology
Place of publication Washington, D.C.
Publication date 2019
ISSN 1098-6596
Keyword(s) Plasmodium
Plasmodium falciparum
antimalarial agents
apicomplexan parasites
drug metabolism
pharmacokinetics
quinazoline
Plasmodium
Plasmodium falciparum
Language eng
DOI 10.1128/AAC.01804-18
Field of Research 0605 Microbiology
1108 Medical Microbiology
1115 Pharmacology And Pharmaceutical Sciences
HERDC Research category C1.1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2019, American Society for Microbiology
Persistent URL http://hdl.handle.net/10536/DRO/DU:30118945

Document type: Journal Article
Collection: School of Life and Environmental Sciences
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