A review of the management of cerebral vasospasm after aneurysmal subarachnoid hemorrhage

Li, Kenny, Barras, Christen D, Chandra, Ronil V, Kok, Hong Kuan, Maingard, Julian T, Carter, Nicole S, Russell, Jeremy H, Lai, Leon, Brooks, Mark and Asadi, Hamed 2019, A review of the management of cerebral vasospasm after aneurysmal subarachnoid hemorrhage, World neurosurgery, vol. 126, pp. 513-527, doi: 10.1016/j.wneu.2019.03.083.

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Title A review of the management of cerebral vasospasm after aneurysmal subarachnoid hemorrhage
Author(s) Li, Kenny
Barras, Christen D
Chandra, Ronil V
Kok, Hong KuanORCID iD for Kok, Hong Kuan orcid.org/0000-0002-8740-6067
Maingard, Julian T
Carter, Nicole S
Russell, Jeremy H
Lai, Leon
Brooks, Mark
Asadi, HamedORCID iD for Asadi, Hamed orcid.org/0000-0003-2475-9727
Journal name World neurosurgery
Volume number 126
Start page 513
End page 527
Total pages 15
Publisher Elsevier
Place of publication Amsterdam, The Netherlands
Publication date 2019-06
ISSN 1878-8769
Keyword(s) Aneurysmal subarachnoid haemorrhage
delayed cerebral ischaemia
delayed ischaemic neurologic deficits
intra-arterial vasodilator
transluminal balloon angioplasty
Summary BACKGROUND: Despite decades of research, cerebral vasospasm (CV) continues to account for high morbidity and mortality in patients who survive their initial aneurysm subarachnoid haemorrhage (aSAH). OBJECTIVE: To define the scope of the problem and review key treatment strategies that have shaped the way cerebral vasospasm is managed in the contemporary era. METHODS: A literature search of cerebral vasospasm management after aneurysmal subarachnoid haemorrhage was performed. RESULTS: Recent advances in neuroimaging have led to an improved detection of vasospasm, but established treatment guidelines including haemodynamic augmentation and interventional procedures remain highly variable among neurosurgical centres. Experimental research in SAH continues to identify novel targets for therapy. CONCLUSIONS: Proactive and preventative strategies such as oral nimodipine and endovascular rescue therapies can reduce the morbidity and mortality associated with CV.
Language eng
DOI 10.1016/j.wneu.2019.03.083
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2019, Elsevier Inc.
Persistent URL http://hdl.handle.net/10536/DRO/DU:30120695

Document type: Journal Article
Collections: Faculty of Health
School of Medicine
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