Anticonvulsant prophylaxis and steroid use in adults with metastatic brain tumors: summary of SNO and ASCO endorsement of the Congress of Neurological Surgeons guidelines

Chang, Susan M., Messersmith, Hans, Ahluwalia, Manmeet, Andrews, David, Brastianos, Priscilla K., Gaspar, Laurie E., Gatson, Na Tosha N., Jordan, Justin T., Khasraw, Mustafa, Lassman, Andrew B., Maues, Julia, Mrugala, Maciej, Raizer, Jeffrey, Schiff, David, Stevens, Glen, Sumrall, Ashley, Van den Bent, Martin and Vogelbaum, Michael A. 2019, Anticonvulsant prophylaxis and steroid use in adults with metastatic brain tumors: summary of SNO and ASCO endorsement of the Congress of Neurological Surgeons guidelines, Neuro-Oncology, vol. 21, no. 4, pp. 424-427, doi: 10.1093/neuonc/noz034.

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Title Anticonvulsant prophylaxis and steroid use in adults with metastatic brain tumors: summary of SNO and ASCO endorsement of the Congress of Neurological Surgeons guidelines
Author(s) Chang, Susan M.
Messersmith, Hans
Ahluwalia, Manmeet
Andrews, David
Brastianos, Priscilla K.
Gaspar, Laurie E.
Gatson, Na Tosha N.
Jordan, Justin T.
Khasraw, MustafaORCID iD for Khasraw, Mustafa orcid.org/0000-0003-3249-9849
Lassman, Andrew B.
Maues, Julia
Mrugala, Maciej
Raizer, Jeffrey
Schiff, David
Stevens, Glen
Sumrall, Ashley
Van den Bent, Martin
Vogelbaum, Michael A.
Journal name Neuro-Oncology
Volume number 21
Issue number 4
Start page 424
End page 427
Total pages 4
Publisher Oxford Academic
Place of publication Oxford, Eng.
Publication date 2019-04
ISSN 1523-5866
Summary BACKGROUND: The Congress of Neurological Surgeons (CNS) has developed a series of guidelines on the treatment of adults with metastatic brain tumors, including systemic therapy and supportive care topics. ASCO has a policy and set of procedures for endorsing clinical practice guidelines that have been developed by other professional organizations. METHODS: Two CNS Guidelines were reviewed for developmental rigor by methodologists and an independent multi-disciplinary Expert Panel was formed to review the content and assess agreement with the recommendations. The expert panel voted to endorse the two guidelines and ASCO and SNO independently reviewed and approved the ASCO/SNO guideline endorsement. RESULTS: The ASCO/SNO Expert Panel determined that the recommendations from the CNS anticonvulsants and steroids guidelines, published January 9, 2019, are clear, thorough, and based upon the most relevant scientific evidence. ASCO/SNO endorsed these two CNS guidelines, with minor alterations. CONCLUSIONS: Key recommendations include: prophylactic anti-epileptic drugs were not recommended for routine use; corticosteroids (specifically dexamethasone) were recommended for temporary symptomatic relief in patients with neurologic symptoms and signs related to mass effect from brain metastases.
Language eng
DOI 10.1093/neuonc/noz034
Field of Research 1109 Neurosciences
1112 Oncology and Carcinogenesis
HERDC Research category C2 Other contribution to refereed journal
Copyright notice ©2019, Society for Neuro-Oncology and the American Society of Clinical Oncology.
Persistent URL http://hdl.handle.net/10536/DRO/DU:30120715

Document type: Journal Article
Collections: Faculty of Health
School of Medicine
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