The effect of blueberry interventions on cognitive performance and mood: a systematic review of randomized controlled trials

Travica, Nikolaj, D'Cunha, Nathan M., Naumovski, Nenad, Kent, Katherine, Mellor, Duane D., Firth, Joseph, Georgousopoulou, Ekavi N., Dean, Olivia, Loughman, Amy, Jacka, Felice and Marx, Wolfgang 2019, The effect of blueberry interventions on cognitive performance and mood: a systematic review of randomized controlled trials, Brain, behavior and immunity, doi: 10.1016/j.bbi.2019.04.001.

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Title The effect of blueberry interventions on cognitive performance and mood: a systematic review of randomized controlled trials
Author(s) Travica, Nikolaj
D'Cunha, Nathan M.
Naumovski, Nenad
Kent, Katherine
Mellor, Duane D.
Firth, Joseph
Georgousopoulou, Ekavi N.
Dean, OliviaORCID iD for Dean, Olivia
Loughman, AmyORCID iD for Loughman, Amy
Jacka, FeliceORCID iD for Jacka, Felice
Marx, WolfgangORCID iD for Marx, Wolfgang
Journal name Brain, behavior and immunity
Total pages 10
Publisher Elsevier
Place of publication Amsterdam, The Netherlands
Publication date 2019-04-15
ISSN 1090-2139
Keyword(s) Anthocyanins
Summary Blueberries are rich in polyphenols that may be beneficial to cognitive performance and mood. The aim of this systematic review was to evaluate randomized controlled trials investigating the effects of blueberries and blueberry products on measures of cognition and mood. In total, eleven articles (that included 12 studies) were identified using freeze-dried blueberries (n = 9 studies), whole blueberries (n = 2) and blueberry concentrate (n = 1). These studies were conducted in children (n = 5), young adults (n = 1), and older people with either no known cognitive impairment (n = 4) or indicated cognitive impairment (n = 2). Eight studies reported blueberry consumption or supplementation at various doses and time lengths to improve measures of cognitive performance, particularly short- and long-term memory and spatial memory. For mood, one study reported significant between-group improvements in positive affect from blueberry products, whereas four studies reported no improvement. Low risk of bias were observed across all studies. Based on the current evidence, blueberries may improve some measures of cognitive performance. However, considerable differences in study design, dosages, and anthocyanin content hinder between-study comparison. The use of standardized blueberry interventions, consideration of placebo formulations, and consistently reported cognitive performance tools are recommended in future trials. PROSPERO registration no. CRD42018100888.
Notes In Press
Language eng
DOI 10.1016/j.bbi.2019.04.001
Indigenous content off
Field of Research 1107 Immunology
1109 Neurosciences
1701 Psychology
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2019, Elsevier
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Document type: Journal Article
Collections: Faculty of Health
School of Exercise and Nutrition Sciences
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