An instrument for the rapid quantification of PM-bound ROS: the particle into nitroxide quencher (PINQ)

Brown, Reece A., Stevanovic, Svetlana, Bottle, Steven and Ristovski, Zoran D. 2019, An instrument for the rapid quantification of PM-bound ROS: the particle into nitroxide quencher (PINQ), Atmospheric measurement techniques, vol. 12, no. 4, pp. 2387-2401, doi: 10.5194/amt-12-2387-2019.

Attached Files
Name Description MIMEType Size Downloads

Title An instrument for the rapid quantification of PM-bound ROS: the particle into nitroxide quencher (PINQ)
Author(s) Brown, Reece A.
Stevanovic, SvetlanaORCID iD for Stevanovic, Svetlana orcid.org/0000-0002-9472-0169
Bottle, Steven
Ristovski, Zoran D.
Journal name Atmospheric measurement techniques
Volume number 12
Issue number 4
Start page 2387
End page 2401
Total pages 15
Publisher Copernicus Publications
Place of publication Goettingen, Germany
Publication date 2019-04-16
ISSN 1867-1381
1867-8548
Keyword(s) Science & Technology
Physical Sciences
Meteorology & Atmospheric Sciences
OXYGEN SPECIES ROS
MICROFLUIDIC ELECTROCHEMICAL SENSOR
AIRBORNE PARTICULATE MATTER
DITHIOTHREITOL DTT ASSAY
PROFLUORESCENT NITROXIDES
ULTRAFINE PARTICLES
OXIDATIVE STRESS
AIR-POLLUTION
RESPIRATORY HEALTH
ONLINE INSTRUMENT
Summary © Author(s) 2019. This work is distributed under the Creative Commons Attribution 4.0 License. Reactive oxygen species (ROS) present on or generated by particulate matter (PM) have been implicated in PM-induced health effects. Methodologies to quantify ROS concentrations vary widely, both in detection and collection methods. However, there is currently an increasing emphasis on rapid collection and measurement due to observations of short half-life ROS. To address this problem, this paper details the design and characterization of a novel instrument for the measurement of PM-bound ROS named the Particle Into Nitroxide Quencher (PINQ). This instrument combines the 9,10-bis (phenylethynyl) anthracene-nitroxide (BPEAnit) ROS assay in conjunction with a purpose-built aerosol collection device, the insoluble aerosol collector (IAC). The IAC continuously collects PM regardless of size or chemistry directly into a liquid sample with a collection efficiency of > 0.97 and a cut-off size of < 20 nm. The sampling time resolution of the PINQ is 1 min, with a limit of detection (LOD) of 0.08 nmol mĝ'3 in equivalent BPEAnit-Me concentration per volume of air. This high sample time resolution and sensitivity is achieved due to a combination of the highly concentrated IAC liquid sample, minimized liquid sample volume, and the rapid reaction and stability of the BPEAnit probe.
Language eng
DOI 10.5194/amt-12-2387-2019
Field of Research 0401 Atmospheric Sciences
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2019, The Authors
Persistent URL http://hdl.handle.net/10536/DRO/DU:30121580

Connect to link resolver
 
Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved.

Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 0 times in TR Web of Science
Scopus Citation Count Cited 0 times in Scopus
Google Scholar Search Google Scholar
Access Statistics: 0 Abstract Views, 0 File Downloads  -  Detailed Statistics
Created: Wed, 15 May 2019, 11:42:11 EST

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.