Combining approach bias modification with working memory training during inpatient alcohol withdrawal: an open-label pilot trial of feasibility and acceptability

Manning, Victoria, Mroz, Katherine, Garfield, Joshua BB, Staiger, Petra K, Hall, Kate, Lubman, Dan I and Verdejo-Garcia, Antonio 2019, Combining approach bias modification with working memory training during inpatient alcohol withdrawal: an open-label pilot trial of feasibility and acceptability, Substance abuse treatment, prevention, and policy, vol. 14, pp. 1-6, doi: 10.1186/s13011-019-0209-2.

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Title Combining approach bias modification with working memory training during inpatient alcohol withdrawal: an open-label pilot trial of feasibility and acceptability
Author(s) Manning, Victoria
Mroz, Katherine
Garfield, Joshua BB
Staiger, Petra KORCID iD for Staiger, Petra K orcid.org/0000-0002-6968-5015
Hall, KateORCID iD for Hall, Kate orcid.org/0000-0001-8648-0313
Lubman, Dan I
Verdejo-Garcia, Antonio
Journal name Substance abuse treatment, prevention, and policy
Volume number 14
Article ID 24
Start page 1
End page 6
Total pages 6
Publisher BioMed Central
Place of publication London, Eng.
Publication date 2019-06-06
ISSN 1747-597X
Keyword(s) Alcohol use disorder
Approach bias
Cognitive bias
Cognitive training
Detoxification
Withdrawal
Working memory
Science & Technology
Life Sciences & Biomedicine
Substance Abuse
Summary BACKGROUND: According to contemporary neurocognitive models, addiction is maintained by the biasing of information-processing and decision-making systems towards relatively automatic, impulsive, reward-seeking responses to drug-related stimuli, and away from more controlled, deliberative, "reflective" states of processing that could result in decisions to delay or avoid drug use. Cognitive training programs aimed at either countering "impulsive" processing or enhancing "reflective" processing alone have shown promise. However, there has been no attempt to simultaneously target both aspects of processing with a combined training program. We aimed to test the feasibility and acceptability of a novel 'dual-training' program targeting both processes during residential alcohol withdrawal, and to measure abstinence rates following discharge. METHODS: Thirty-seven patients undergoing alcohol withdrawal at a residential unit participated in this open-label pilot feasibility study. We tested a 4-session program of dual cognitive training targeting both impulsive (approach bias) and reflective (working memory) aspects of processing. Descriptive statistics were used to examine feasibility (training uptake and completion rates) and acceptability (withdrawal from the study; participants' ratings of the tasks). Alcohol abstinence rates were examined 2-weeks post-discharge. RESULTS: Seven participants withdrew after commencing training. Twenty-six (70%) completed the 4-session training protocol, and four completed 3 sessions before discharging. Among participants who provided ratings, nearly all (93%) rated the training as interesting. Most (87%) indicated that they felt it had improved their attention. However, most did not feel it had decreased their craving for alcohol. At 2-weeks post-discharge, 16 (53%) participants reported abstaining from alcohol. For comparison, an earlier pilot trial in the same setting found a 68% abstinence rate with approach bias training alone, and 47% abstinence in a non-training control group. CONCLUSIONS: Dual training during residential alcohol detoxification appears to be both acceptable and feasible, suggesting that future research is warranted to test its effectiveness at reducing likelihood of relapse.
Language eng
DOI 10.1186/s13011-019-0209-2
Indigenous content off
Field of Research 1701 Psychology
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2019, The Author(s)
Persistent URL http://hdl.handle.net/10536/DRO/DU:30122627

Document type: Journal Article
Collections: Faculty of Health
School of Psychology
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