Openly accessible

Moderate physical training ameliorates cardiovascular dysfunction induced by high fat diet after cessation of training in adult rats

Tófolo, Laize Peron, Rinaldi, Wilson, Gôngora, Adriane Barreto, Ianoni Matiusso, Camila Cristina, Pavanello, Audrei, Malta, Ananda, De Almeida, Douglas Lopes, Ribeiro, Tatiane Aparecida, Oliveira, Anna R., Chimirri Peres, Maria Natalia, Armitage, James, De Freitas Mathias, Paulo Cezar and Palma-Rigo, Kesia 2019, Moderate physical training ameliorates cardiovascular dysfunction induced by high fat diet after cessation of training in adult rats, Frontiers in physiology, vol. 10, no. MAR, doi: 10.3389/fphys.2019.00170.

Attached Files
Name Description MIMEType Size Downloads

Title Moderate physical training ameliorates cardiovascular dysfunction induced by high fat diet after cessation of training in adult rats
Author(s) Tófolo, Laize Peron
Rinaldi, Wilson
Gôngora, Adriane Barreto
Ianoni Matiusso, Camila Cristina
Pavanello, Audrei
Malta, Ananda
De Almeida, Douglas Lopes
Ribeiro, Tatiane Aparecida
Oliveira, Anna R.
Chimirri Peres, Maria Natalia
Armitage, JamesORCID iD for Armitage, James orcid.org/0000-0002-3762-0911
De Freitas Mathias, Paulo Cezar
Palma-Rigo, Kesia
Journal name Frontiers in physiology
Volume number 10
Issue number MAR
Article ID 170
Total pages 11
Publisher Frontiers Media
Place of publication Lausanne, Switzerland
Publication date 2019-03-12
ISSN 1664-042X
Summary © 2019 Tófolo, Rinaldi, Gôngora, Matiusso, Pavanello, Malta, de Almeida, Ribeiro, Oliveira, Peres, Armitage, Mathias and Palma-Rigo. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. We aimed to test whether moderate physical training can induce long-lasting protection against cardiovascular risk factors induced by high fat diet (HFD) intake, even after cessation of training. 90-days-old Wistar rats were submitted to a sedentary lifestyle or moderate physical training, three times a week, for 30 days. Following this, at 120 days-of age, sedentary and trained rats received a hypercaloric diet (HFD) or a commercial diet normal fat diet (NFD) for 30 days. Body weight (BW) and food intake were evaluated weekly. At 150 days-of age, hemodynamic measures (systolic, diastolic, mean blood pressure, pulse pressure, pulse interval and heart rate) were made via an indwelling femoral artery catheter. Beat-to-beat data were analyzed to calculate power spectra of systolic blood pressure (SBP) and pulse interval. After euthanasia, mesenteric fat pads were removed and weighted and total blood was stored for later analysis of lipid profile. Consumption of a HFD increased blood pressure (BP), pulse pressure, low frequency BP variability, BW gain, fat pad stores and induced dyslipidemia. Interestingly, prior physical training was able to partially protect against this rise in BP and body fat stores. Prior physical training did not totally protect against the effects of HFD consumption but previously trained animals did demonstrate resistance to the development of cardiometabolic alterations, which illustrate that the benefits of physical training may be partially maintained even after 30 days of detraining period.
Language eng
DOI 10.3389/fphys.2019.00170
Indigenous content off
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2019, Tófolo, Rinaldi, Gôngora, Matiusso, Pavanello, Malta, de Almeida, Ribeiro, Oliveira, Peres, Armitage, Mathias and Palma-Rigo
Free to Read? Yes
Persistent URL http://hdl.handle.net/10536/DRO/DU:30122867

Document type: Journal Article
Collections: Faculty of Health
School of Medicine
Open Access Collection
Connect to link resolver
 
Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved.

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.

Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 0 times in TR Web of Science
Scopus Citation Count Cited 1 times in Scopus
Google Scholar Search Google Scholar
Access Statistics: 97 Abstract Views, 0 File Downloads  -  Detailed Statistics
Created: Fri, 14 Jun 2019, 14:17:05 EST

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.