Dissolution-modulating mechanism of alkalizers and polymers in a nanoemulsifying solid dispersion containing ionizable and poorly water-soluble drug

Tran, Thao Truong-Dinh, Tran, Phuong Ha-Lien and Lee, Beom-Jin 2009, Dissolution-modulating mechanism of alkalizers and polymers in a nanoemulsifying solid dispersion containing ionizable and poorly water-soluble drug, European Journal of Pharmaceutics and Biopharmaceutics, vol. 72, no. 1, pp. 83-90, doi: 10.1016/j.ejpb.2008.12.009.

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Title Dissolution-modulating mechanism of alkalizers and polymers in a nanoemulsifying solid dispersion containing ionizable and poorly water-soluble drug
Author(s) Tran, Thao Truong-Dinh
Tran, Phuong Ha-LienORCID iD for Tran, Phuong Ha-Lien orcid.org/0000-0001-8463-7516
Lee, Beom-Jin
Journal name European Journal of Pharmaceutics and Biopharmaceutics
Volume number 72
Issue number 1
Start page 83
End page 90
Total pages 8
Publisher Elsevier
Place of publication Amsterdam, The Netherlands
Publication date 2009-05
ISSN 0939-6411
Keyword(s) Dissolution-modulating mechanism
Nanoemulsifying solid dispersion
Alkalizers
Crystalline structure
Microenvironmental pH
Spring-like precipitation
Science & Technology
Life Sciences & Biomedicine
Pharmacology & Pharmacy
WEAKLY BASIC DRUG
MATRIX TABLETS
DELIVERY-SYSTEMS
BIOAVAILABILITY
RELEASE
ENHANCEMENT
FORMULATION
EXCIPIENTS
PIROXICAM
Language eng
DOI 10.1016/j.ejpb.2008.12.009
Indigenous content off
Field of Research 1115 Pharmacology and Pharmaceutical Sciences
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©2008, Elsevier B.V.
Persistent URL http://hdl.handle.net/10536/DRO/DU:30125336

Document type: Journal Article
Collections: Faculty of Health
School of Medicine
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