Resection of peritoneal metastases causing malignant small bowel obstruction

Abbas, Saleh M and Merrie, Arend EH 2007, Resection of peritoneal metastases causing malignant small bowel obstruction, World journal of surgical oncology, vol. 5, pp. 1-4, doi: 10.1186/1477-7819-5-122.

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Title Resection of peritoneal metastases causing malignant small bowel obstruction
Author(s) Abbas, Saleh MORCID iD for Abbas, Saleh M
Merrie, Arend EH
Journal name World journal of surgical oncology
Volume number 5
Article ID 122
Start page 1
End page 4
Total pages 4
Publisher BioMed Central
Place of publication London, Eng.
Publication date 2007
ISSN 1477-7819
Keyword(s) Colorectal Cancer
Small Bowel Obstruction
Peritoneal Metastasis
Small Bowel Resection
Resectable Disease
Summary Background: Resection of peritoneal metastases has been shown to improve survival in patients with abdominal metastatic disease from abdominal or extra abdominal malignancy. This study evaluates the benefit of peritoneal metastatic resection in patients with malignant small bowel obstruction and a past history of treated cancer. Patients and methods: Patients undergoing laparotomy for resection of peritoneal metastases from recurrence of previous cancer between 1992-2003 were reviewed retrospectively. Data were collected about type of primary cancer, interval to recurrence, extent of the disease and completeness of resection, morbidity and mortality and long-term survival. Results: Between 1992 and 2003 there were 79 patients (median age 62, range 19-91) who had laparotomy for small bowel obstruction due to recurrent cancer. The primary cancer was colorectal (31), gynaecologic cancer (19), melanoma (16) and others (13). Overall, the rate of complications was 35% and mortality was 10%. Median survival was 5 months; patients with history of colorectal cancer had better survival than other cancer (median survival 7 months vs. 4 months; p = 0.02). Multivariate analysis showed that the extent of recurrent disease was the only factor that affected overall survival. Conclusion: Laparotomy for small bowel obstruction is a worthwhile option for patients with malignant small bowel obstruction. Although it is associated with significant morbidity and mortality it offers a reasonable survival benefit in particular for patients with completely resectable disease.
Language eng
DOI 10.1186/1477-7819-5-122
Indigenous content off
Field of Research 1103 Clinical Sciences
1112 Oncology and Carcinogenesis
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©2007, Abbas and Merrie
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