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Determinants of drug-related problems among ambulatory type 2 diabetes patients with hypertension comorbidity in Southwest Ethiopia: a prospective cross sectional study

Yimama, M, Jarso, H and Desse, Tigestu Alemu 2018, Determinants of drug-related problems among ambulatory type 2 diabetes patients with hypertension comorbidity in Southwest Ethiopia: a prospective cross sectional study, BMC Research Notes, vol. 11, no. 1, pp. 1-6, doi: 10.1186/s13104-018-3785-8.


Title Determinants of drug-related problems among ambulatory type 2 diabetes patients with hypertension comorbidity in Southwest Ethiopia: a prospective cross sectional study
Author(s) Yimama, M
Jarso, H
Desse, Tigestu AlemuORCID iD for Desse, Tigestu Alemu orcid.org/0000-0002-6116-0433
Journal name BMC Research Notes
Volume number 11
Issue number 1
Article ID 679
Start page 1
End page 6
Total pages 6
Publisher BMC
Place of publication London, Eng.
Publication date 2018-09-24
ISSN 1756-0500
Keyword(s) Type 2 diabetes
Hypertension
Drug-related problems
Ethiopia
Summary Objective:The aim of this study was to assess drug-related problems and its determinants in type 2 diabetes patients with hypertension co-morbidity. Results: A total of 300 type 2 diabetes patients with hypertension co-morbidity were studied. The majority of participants, 194 (64.7%), were males. Mean age of the participants was 54.44 ± 11.68 years. The mean durations of diabetes and hypertension were 5.37 ± 4.79 and 5.15 ± 4.65 years respectively. The most commonly prescribed antidiabetic medications were metformin in 200 (66.7%) and insulin 126 (42%) of the participants. Enalapril was the most commonly prescribed antihypertensive medication; 272 (90.7%). Aspirin was prescribed to 182 (60.7%) participants. Statins were prescribed to one-third (65.67%) of the participants. Eighty-five (28.3%) participants had diabetes related complications other than hypertension. A total of 494 drug related problems were identified. The mean number of drug related problems was 1.65 ± 1.05. The most common drug related problems were need for additional drug therapy (29.35%), ineffective drug (27.94%) and dose too low (15.8%). Independent predictors of drug related problems were age 41–60 years (AOR = 6.87, 95% CI 2.63–17.93), age > 60 years (AOR = 5.85, 95% CI 2.15–15.93) and the presence of comorbidity (AOR = 3.0, 95% CI 1.11–8.16).
Language eng
DOI 10.1186/s13104-018-3785-8
Indigenous content off
Field of Research 0601 Biochemistry and Cell Biology
1199 Other Medical and Health Sciences
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2018, The Authors
Free to Read? Yes
Use Rights Creative Commons Attribution licence
Persistent URL http://hdl.handle.net/10536/DRO/DU:30129151

Document type: Journal Article
Collections: Faculty of Health
School of Nursing and Midwifery
Open Access Collection
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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.