Prevalence of goiter among children in Ethiopia and associated factors: A systematic review and meta-analysis

Dessie, Getenet, Amare, Desalegne, Dagnew, Amare Belachew, Mulugeta, Henok, Kassa, Dessalegn Haile, Negesse, Ayenew, Kassa, Getachew Mullu, Wagnew, Fasil, Islam, Sheikh Mohammed Shariful and Burrowes, Sahai 2019, Prevalence of goiter among children in Ethiopia and associated factors: A systematic review and meta-analysis, BMC Public Health, vol. 19, no. 1, pp. 1-13, doi: 10.1186/s12889-019-7505-7.

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Title Prevalence of goiter among children in Ethiopia and associated factors: A systematic review and meta-analysis
Author(s) Dessie, Getenet
Amare, Desalegne
Dagnew, Amare Belachew
Mulugeta, Henok
Kassa, Dessalegn Haile
Negesse, Ayenew
Kassa, Getachew Mullu
Wagnew, Fasil
Islam, Sheikh Mohammed SharifulORCID iD for Islam, Sheikh Mohammed Shariful
Burrowes, Sahai
Journal name BMC Public Health
Volume number 19
Issue number 1
Start page 1
End page 13
Total pages 13
Publisher Springer Nature
Place of publication London, Eng.
Publication date 2019-08-29
ISSN 1471-2458
Keyword(s) Children
Summary Background: The distribution of goiter among children and its risk factors are not well investigated in Ethiopia. Therefore, this systematic review and meta-analysis was designed to determine the pooled prevalence of goiter and its associated factors among children in Ethiopia. Methods: Electronic web-based searches of PubMed, Google Scholar, EMBASE, and the World Health Organization's Hinari portal (which includes the SCOPUS, African Index Medicus, and African Journals Online databases) were conducted to find primary studies. Relevant data were extracted and descriptive summaries of the studies were presented in tables. The I2 statistic was used to assess heterogeneity across studies. Funnel plot asymmetry and Egger's tests were used to check for publication bias. A random effects model was used to estimate the pooled prevalence of goiter. Odds ratios (OR) with 95% Confidence Intervals (CI) were also used to determine the association of identified variables with goiter. All statistical analyses were conducted using Stata version 14 software. Results: Our search identified 982 studies, of which, 19 articles were eligible for inclusion in the final meta-analysis. The pooled estimate of goiter among children in Ethiopia was 40.50% (95% CI: 33.6-47.40). The regional distribution of goiter ranged from 44.22 (95% CI: 17.44-71) in Southern Nations Nationalities and Peoples' Region, to 32.79% (95% CI: 19.86-45.73) in Benishangul Gumez region. The prevalence of goiter among female children (44.34%) was higher than among male (32.88%) children. Goiter prevalence was also significantly higher among children who consumed vegetables three or more times per week OR = 1.3 (95% CI: 1.02-1.66); those who had family history of goiter, OR = 2.38 (95% CI: 1.9-2.99); and those whose family stored salt near to fires, OR = 1.4 l (95% CI: 1.1-1.79). Conclusion: The prevalence of goiter among children in Ethiopia was high, and endemic according to the WHO criteria. Our findings suggest the need for interventions to improve salt iodization, and for improved health education on appropriate salt storage. In addition, more research may be needed to improve our understanding of foods that increase the risk of goiter among children.
Language eng
DOI 10.1186/s12889-019-7505-7
Indigenous content off
Field of Research 1117 Public Health and Health Services
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2019, The Author(s)
Free to Read? Yes
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Document type: Journal Article
Collections: Faculty of Health
School of Exercise and Nutrition Sciences
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