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Protocol for economic evaluation alongside a cluster-randomised controlled trial of a psychoeducational intervention for the primary prevention of postnatal mental health problems in first-time mothers

Ride, Jemimah, Rowe, Heather, Wynter, Karen, Fisher, Jane and Lorgelly, Paula 2014, Protocol for economic evaluation alongside a cluster-randomised controlled trial of a psychoeducational intervention for the primary prevention of postnatal mental health problems in first-time mothers, BMJ open, vol. 4, no. 10, doi: 10.1136/bmjopen-2014-006226.

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Title Protocol for economic evaluation alongside a cluster-randomised controlled trial of a psychoeducational intervention for the primary prevention of postnatal mental health problems in first-time mothers
Author(s) Ride, Jemimah
Rowe, Heather
Wynter, KarenORCID iD for Wynter, Karen orcid.org/0000-0003-4620-7691
Fisher, Jane
Lorgelly, Paula
Journal name BMJ open
Volume number 4
Issue number 10
Total pages 7
Publisher BMJ Publishing
Place of publication London, Eng.
Publication date 2014-10
ISSN 2044-6055
Keyword(s) Science & Technology
Life Sciences & Biomedicine
Medicine, General & Internal
General & Internal Medicine
COST-EFFECTIVENESS ANALYSIS
POSTPARTUM DEPRESSION
SAMPLE-SIZE
EQ-5D
ANXIETY
RESPONSIVENESS
UNCERTAINTY
UTILITIES
IMPACT
WOMEN
HEALTH ECONOMICS
MENTAL HEALTH
PUBLIC HEALTH
Summary Introduction: Postnatal mental health problems, which are an international public health priority, are a suitable target for preventive approaches. The financial burden of these disorders is borne across sectors in society, including health, early childhood, education, justice and the workforce. This paper describes the planned economic evaluation of What Were We Thinking, a psychoeducational intervention for the prevention of postnatal mental health problems in firsttime mothers.Methods and analysis: The evaluation will be conducted alongside a cluster-randomised controlled trial of its clinical effectiveness. Cost-effectiveness and costs-utility analyses will be conducted, resulting in estimates of cost per percentage point reduction in combined 30-day prevalence of depression, anxiety and adjustment disorders and cost per quality-adjusted life year gained. Uncertainty surrounding these estimates will be addressed using non-parametric bootstrapping and represented using cost-effectiveness acceptability curves. Additional cost analyses relevant for implementation will also be conducted. Modelling will be employed to estimate longer term costeffectiveness if the intervention is found to be clinically effective during the period of the trial.Ethics and dissemination: Approval to conduct the study was granted by the Southern Health (now Monash Health) Human Research Ethics Committee (24 April 2013; 11388B). The study was registered with the Monash University Human Research Ethics Committee (30 April 2013; CF12/1022-2012000474). The Education and Policy Research Committee, Victorian Government Department of Education and Early Childhood Development approved the study (22 March 2012; 2012-001472). Use of the EuroQol was registered with the EuroQol Group; 16 August 2012.Trial registration number: The trial was registered with the Australian New Zealand Clinical Trials Registry on 7 May 2012 (registration number ACTRN12613000506796).
Language eng
DOI 10.1136/bmjopen-2014-006226
Indigenous content off
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2014, The Authors
Free to Read? Yes
Persistent URL http://hdl.handle.net/10536/DRO/DU:30129875

Document type: Journal Article
Collections: Faculty of Health
School of Nursing and Midwifery
Open Access Collection
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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.