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Loss of dihydrotestosterone-inactivation activity promotes prostate cancer castration resistance detectable by functional imaging

Zhu, Ziqi, Chung, Yoon-Mi, Sergeeva, Olga, Kepe, Vladimir, Berk, Michael, Li, Jianneng, Ko, Hyun-Kyung, Li, Zhenfei, Petro, Marianne, DiFilippo, Frank P., Lee, Zhenghong and Sharifi, Nima 2018, Loss of dihydrotestosterone-inactivation activity promotes prostate cancer castration resistance detectable by functional imaging, Journal of biological chemistry, vol. 293, no. 46, pp. 17829-17837, doi: 10.1074/jbc.RA118.004846.

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Title Loss of dihydrotestosterone-inactivation activity promotes prostate cancer castration resistance detectable by functional imaging
Author(s) Zhu, Ziqi
Chung, Yoon-Mi
Sergeeva, Olga
Kepe, Vladimir
Berk, MichaelORCID iD for Berk, Michael orcid.org/0000-0002-5554-6946
Li, Jianneng
Ko, Hyun-Kyung
Li, Zhenfei
Petro, Marianne
DiFilippo, Frank P.
Lee, Zhenghong
Sharifi, Nima
Journal name Journal of biological chemistry
Volume number 293
Issue number 46
Start page 17829
End page 17837
Total pages 9
Publisher American Society for Biochemistry and Molecular Biology
Place of publication Bethesda, Md.
Publication date 2018-11-16
ISSN 1083-351X
Keyword(s) Science & Technology
Life Sciences & Biomedicine
Biochemistry & Molecular Biology
steroid
steroid hormone receptor
steroidogenesis
metabolism
metabolic regulation
androgen
uridine 5'-diphospho-glucuronosyltransferase (UDP-glucuronosyltransferase)
castration-resistant prostate cancer
nuclear medicine
PET
prostate cancer
ANDROGEN RECEPTOR
UDP-GLUCURONOSYLTRANSFERASES
TESTOSTERONE
GLUCURONIDATION
PROGRESSION
ABIRATERONE
METASTASIS
EXPRESSION
Language eng
DOI 10.1074/jbc.RA118.004846
Indigenous content off
Field of Research 06 Biological Sciences
11 Medical and Health Sciences
03 Chemical Sciences
HERDC Research category C1 Refereed article in a scholarly journal
Free to Read? Yes
Persistent URL http://hdl.handle.net/10536/DRO/DU:30130070

Document type: Journal Article
Collections: Faculty of Health
School of Medicine
Open Access Collection
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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.