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Protocol for establishing a child and adolescent twin register for mental health research and capacity building in Sri Lanka and other low and middle-income countries in South Asia

Jayaweera, Kaushalya, Craig, Jeffrey, Zavos, Helena M. S., Abeysinghe, Nihal, De Alwis, Sunil De, Andras, Alina, Dissanayake, Lasith, Dziedzic, Krysia, Fernando, Buddhika, Glozier, Nick, Hewamalage, Asiri, Ives, Jonathan, Jordan, Kelvin P., Kodituwakku, Godwin, Mallen, Christian, Rahman, Omar, Zafar, Shamsa, Saxena, Alka, Rijsdijk, Fruhling, Saffery, Richard, Simonoff, Emily, Yusuf, Rita and Sumathipala, Athula 2019, Protocol for establishing a child and adolescent twin register for mental health research and capacity building in Sri Lanka and other low and middle-income countries in South Asia, BMJ open, vol. 9, no. 10, doi: 10.1136/bmjopen-2019-029332.

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Title Protocol for establishing a child and adolescent twin register for mental health research and capacity building in Sri Lanka and other low and middle-income countries in South Asia
Author(s) Jayaweera, Kaushalya
Craig, JeffreyORCID iD for Craig, Jeffrey orcid.org/0000-0003-3979-7849
Zavos, Helena M. S.
Abeysinghe, Nihal
De Alwis, Sunil De
Andras, Alina
Dissanayake, Lasith
Dziedzic, Krysia
Fernando, Buddhika
Glozier, Nick
Hewamalage, Asiri
Ives, Jonathan
Jordan, Kelvin P.
Kodituwakku, Godwin
Mallen, Christian
Rahman, Omar
Zafar, Shamsa
Saxena, Alka
Rijsdijk, Fruhling
Saffery, Richard
Simonoff, Emily
Yusuf, Rita
Sumathipala, Athula
Journal name BMJ open
Volume number 9
Issue number 10
Total pages 8
Publisher BMJ Publishing
Place of publication London, Eng.
Publication date 2019-10
ISSN 2044-6055
Keyword(s) Low and Middle Income Countries (LMIC)
South Asia
Sri Lanka
cohort
infant child and adolescents
mental health
twins
We would like to acknowledge the other members of the SEARCH Group
Summary © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY. Published by BMJ. Introduction Worldwide, 10%-20% of children and adolescents experience mental health conditions. However, most such disorders remain undiagnosed until adolescence or adulthood. Little is known about the factors that influence mental health in children and adolescents, especially in low and middle-income countries (LMIC), where environmental threats, such as poverty and war, may affect optimal neurodevelopment. Cohort studies provide important information on risks and resilience across the life course by enabling tracking of the effects of early life environment on health during childhood and beyond. Large birth cohort studies, including twin cohorts that can be aetiologically informative, have been conducted within high-income countries but are not generalisable to LMIC. There are limited longitudinal birth cohort studies in LMIC. Methods We sought to enhance the volume of impactful research in Sri Lanka by establishing a Centre of Excellence for cohort studies. The aim is to establish a register of infant, child and adolescent twins, including mothers pregnant with twins, starting in the districts of Colombo (Western Province) and Vavuniya (Northern Province). We will gain consent from twins or parents for future research projects. This register will provide the platform to investigate the aetiology of mental illness and the impact of challenges to early brain development on future mental health. Using this register, we will be able to conduct research that will (1) expand existing research capacity on child and adolescent mental health and twin methods; (2) further consolidate existing partnerships and (3) establish new collaborations. The initiative is underpinned by three pillars: high-quality research, ethics, and patient and public involvement and engagement (PPIE). Ethics and dissemination Ethical approval for this study was obtained from the Ethics Review Committee of Sri Lanka Medical Association and Keele University's Ethical Review Panel. In addition to journal publications, a range of PPIE activities have been conducted.
Language eng
DOI 10.1136/bmjopen-2019-029332
Indigenous content off
HERDC Research category C1 Refereed article in a scholarly journal
Free to Read? Yes
Persistent URL http://hdl.handle.net/10536/DRO/DU:30132065

Document type: Journal Article
Collections: Faculty of Health
School of Medicine
Open Access Collection
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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.