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Associations between sub-clinical markers of cardiometabolic risk and exposure to residential indoor air pollutants in healthy adults in Perth, western Australia: a study protocol

Gilbey, Suzanne E., Reid, Christopher M., Huxley, Rachel R., Soares, Mario J., Zhao, Yun and Rumchev, Krassi 2019, Associations between sub-clinical markers of cardiometabolic risk and exposure to residential indoor air pollutants in healthy adults in Perth, western Australia: a study protocol, International journal of environmental research and public health, vol. 16, no. 19, doi: 10.3390/ijerph16193548.

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Title Associations between sub-clinical markers of cardiometabolic risk and exposure to residential indoor air pollutants in healthy adults in Perth, western Australia: a study protocol
Author(s) Gilbey, Suzanne E.
Reid, Christopher M.
Huxley, Rachel R.ORCID iD for Huxley, Rachel R. orcid.org/0000-0002-2705-6616
Soares, Mario J.
Zhao, Yun
Rumchev, Krassi
Journal name International journal of environmental research and public health
Volume number 16
Issue number 19
Total pages 14
Publisher MDPI
Place of publication Basel, Switzerland
Publication date 2019-09
ISSN 1661-7827
1660-4601
Keyword(s) Science & Technology
Life Sciences & Biomedicine
Environmental Sciences
Public, Environmental & Occupational Health
Environmental Sciences & Ecology
Indoor air pollution
cardiovascular
metabolic
blood pressure
risk factors
diabetes mellitus
AMBULATORY BLOOD-PRESSURE
FINE PARTICULATE MATTER
LONG-TERM EXPOSURE
CARDIOVASCULAR-DISEASE RISK
POLLUTION EXPOSURE
ENVIRONMENTAL-FACTORS
DOMESTIC EXPOSURE
EUROPEAN-SOCIETY
LIPID MARKERS
HYPERTENSION
Summary © 2019 by the authors. Licensee MDPI, Basel, Switzerland. Background: A growing body of epidemiological and clinical evidence has implicated air pollution as an emerging risk factor for cardiometabolic disease. Whilst individuals spend up to two-thirds of daily time in their domestic residential environment, very few studies have been designed to objectively measure the sub-clinical markers of cardiometabolic risk with exposure to domestic indoor air pollutants. This cross-sectional study aims to investigate associations between the components of domestic indoor air quality and selected sub-clinical cardiometabolic risk factors in a cohort of healthy adults living in Perth,Western Australia. Methods: One hundred and eleven non-smoking adults (65% female) living in non-smoking households who were aged between 35-69 years were recruited for the project. Study subjects were invited to participate in all sections of the study, which included: Domestic indoor air monitoring along with the concurrent 24 h ambulatory monitoring of peripheral and central blood pressure and measures of central hemodynamic indices, standardized questionnaires on aspects relating to current health status and the domestic environment, a 24 h time-activity diary during the monitoring period, and clinic-based health assessment involving collection of blood and urine biomarkers for lipid and glucose profiles, as well as measures of renal function and an analysis of central pulse wave and pulse wave velocity. Results: This study provides a standardized approach to the study of sub-clinical cardiometabolic health effects that are related to the exposure to indoor air pollution. Conclusion: The findings of this study may provide direction for future research that will further contribute to our understanding of the relationship that exists between indoor air pollution and sub-clinical markers of cardiometabolic risk.
Language eng
DOI 10.3390/ijerph16193548
Indigenous content off
Field of Research MD Multidisciplinary
HERDC Research category C1 Refereed article in a scholarly journal
Free to Read? Yes
Persistent URL http://hdl.handle.net/10536/DRO/DU:30132115

Document type: Journal Article
Collections: Faculty of Health
PVC's Office - Health
Open Access Collection
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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.