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Essential requirement for PP2A inhibition by the oncogenic receptor c-KIT suggests PP2A reactivation as a strategy to treat c-KIT+ cancers

Roberts, Kathryn G., Smith, Amanda M., McDougall, Fiona, Carpenter, Helen, Horan, Martin, Neviani, Paolo, Powell, Jason A., Thomas, Daniel, Guthridge, Mark A., Perrotti, Danilo, Sim, Alistair T. R., Ashman, Leonie K. and Verrills, Nicole M. 2010, Essential requirement for PP2A inhibition by the oncogenic receptor c-KIT suggests PP2A reactivation as a strategy to treat c-KIT+ cancers, Cancer Research, vol. 70, no. 13, pp. 5438-5447, doi: 10.1158/0008-5472.CAN-09-2544.

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Title Essential requirement for PP2A inhibition by the oncogenic receptor c-KIT suggests PP2A reactivation as a strategy to treat c-KIT+ cancers
Author(s) Roberts, Kathryn G.
Smith, Amanda M.
McDougall, Fiona
Carpenter, Helen
Horan, Martin
Neviani, Paolo
Powell, Jason A.
Thomas, Daniel
Guthridge, Mark A.ORCID iD for Guthridge, Mark A. orcid.org/0000-0002-0536-3471
Perrotti, Danilo
Sim, Alistair T. R.
Ashman, Leonie K.
Verrills, Nicole M.
Journal name Cancer Research
Volume number 70
Issue number 13
Start page 5438
End page 5447
Total pages 10
Publisher American Association for Cancer Research
Place of publication Philadelphia, Pa.
Publication date 2010-07-01
ISSN 0008-5472
1538-7445
Keyword(s) Science & Technology
Life Sciences & Biomedicine
Oncology
PROTEIN PHOSPHATASE 2A
ACUTE MYELOID-LEUKEMIA
GASTROINTESTINAL STROMAL TUMORS
CHRONIC LYMPHOCYTIC-LEUKEMIA
SERINE/THREONINE PHOSPHATASES
JUXTAMEMBRANE DOMAIN
REDUCED EXPRESSION
IMATINIB MESYLATE
LOW-FREQUENCY
CELL-LINES
Language eng
DOI 10.1158/0008-5472.CAN-09-2544
Indigenous content off
Field of Research 1112 Oncology and Carcinogenesis
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2010, American Association for Cancer Research
Free to Read? Yes
Persistent URL http://hdl.handle.net/10536/DRO/DU:30132372

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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.