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Microencapsulated tuna oil results in higher absorption of DHA in toddlers

Fard, S.G., Loh, S.P., Turchini, Giovanni M., Wang, B., Elliott, G. and Sinclair, A.J. 2020, Microencapsulated tuna oil results in higher absorption of DHA in toddlers, Nutrients, vol. 12, no. 1, pp. 1-15, doi: 10.3390/nu12010248.

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Title Microencapsulated tuna oil results in higher absorption of DHA in toddlers
Author(s) Fard, S.G.
Loh, S.P.
Turchini, Giovanni M.ORCID iD for Turchini, Giovanni M. orcid.org/0000-0003-0694-4283
Wang, B.
Elliott, G.
Sinclair, A.J.
Journal name Nutrients
Volume number 12
Issue number 1
Article ID 248
Start page 1
End page 15
Total pages 15
Publisher MDPI
Place of publication Basel, Switzerland
Publication date 2020
ISSN 2072-6643
2072-6643
Keyword(s) Science & Technology
Life Sciences & Biomedicine
Nutrition & Dietetics
bioavailability
microencapsulation
tuna oil
omega-3
DHA
toddlers
POLYUNSATURATED FATTY-ACIDS
HUMAN BREAST-MILK
FISH-OIL
VISUAL-ACUITY
DOCOSAHEXAENOIC ACID
PRETERM INFANTS
ARACHIDONIC-ACID
DIETARY-INTAKE
CLINICAL-TRIAL
OMEGA-3 INDEX
Summary Docosahexaenoic acid (DHA) is an essential component for brain and visual acuity development during foetal and early postnatal life. A newly released directive under the European Commission stipulates DHA as a mandatory ingredient in infant formula. This poses challenges to manufacturers in preserving the stability and bioavailability of DHA at levels akin to human breast milk. The aims of this study were (a) to investigate the bioavailability of microencapsulated omega-3 DHA formulations in healthy toddlers compared with high DHA fish oil for a one-month period and (b) to assess the effect of DHA supplementation on children’s sleep and cry patterns. Sixty toddlers were randomly allocated to four groups: 1. unfortified formula, 2. unfortified formula plus high DHA tuna oil, 3. fortified formula with dairy-based microencapsulated high DHA tuna oil powder, and 4. fortified formula with allergenic-free microencapsulated high DHA tuna oil powder. Bioavailability was assessed from both blood and faecal fatty acid levels. The results showed an enhanced bioavailability with significantly greater concentrations of blood DHA levels in formulas with microencapsulated powders. There were no significant effects of treatment on sleep and cry patterns. Application and delivery of microencapsulated DHA tuna oil powder in toddlers’ formula provided better bioavailability of the active DHA.
Language eng
DOI 10.3390/nu12010248
Indigenous content off
Field of Research 0908 Food Sciences
1111 Nutrition and Dietetics
HERDC Research category C1 Refereed article in a scholarly journal
Free to Read? Yes
Persistent URL http://hdl.handle.net/10536/DRO/DU:30133914

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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.