A physician-initiated double-blind, randomised, placebo-controlled, phase 2 study evaluating the efficacy and safety of inhibition of NADPH oxidase with the first-in-class Nox-1/4 inhibitor, GKT137831, in adults with type 1 diabetes and persistently eleva

Reutens, Anne T, Jandeleit-Dahm, Karin, Thomas, Merlin, Salim, Agus, De Livera, Alysha M, Bach, Leon A, Colman, Peter G, Davis, Timothy M E, Ekinci, Elif I, Fulcher, Greg, Hamblin, Peter Shane, Kotowicz, Mark A, MacIsaac, Richard J, Morbey, Claire, Simmons, David, Soldatos, Georgia, Wittert, Gary, Wu, Ted, Cooper, Mark E and Shaw, Jonathan E 2020, A physician-initiated double-blind, randomised, placebo-controlled, phase 2 study evaluating the efficacy and safety of inhibition of NADPH oxidase with the first-in-class Nox-1/4 inhibitor, GKT137831, in adults with type 1 diabetes and persistently elevated urinary albumin excretion: Protocol and statistical considerations, Contemporary Clinical Trials, vol. 90, pp. 1-8, doi: 10.1016/j.cct.2019.105892.

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Title A physician-initiated double-blind, randomised, placebo-controlled, phase 2 study evaluating the efficacy and safety of inhibition of NADPH oxidase with the first-in-class Nox-1/4 inhibitor, GKT137831, in adults with type 1 diabetes and persistently elevated urinary albumin excretion: Protocol and statistical considerations
Author(s) Reutens, Anne T
Jandeleit-Dahm, Karin
Thomas, Merlin
Salim, Agus
De Livera, Alysha M
Bach, Leon A
Colman, Peter G
Davis, Timothy M E
Ekinci, Elif I
Fulcher, Greg
Hamblin, Peter Shane
Kotowicz, Mark AORCID iD for Kotowicz, Mark A orcid.org/0000-0002-8094-1411
MacIsaac, Richard J
Morbey, Claire
Simmons, David
Soldatos, Georgia
Wittert, Gary
Wu, Ted
Cooper, Mark E
Shaw, Jonathan E
Journal name Contemporary Clinical Trials
Volume number 90
Article ID 105892
Start page 1
End page 8
Total pages 8
Publisher Elsevier
Place of publication Amsterdam, The Netherlands
Publication date 2020-03-01
ISSN 1551-7144
1559-2030
Keyword(s) Diabetic nephropathy
NADPH oxidase
Type 1 diabetes
Albuminuria
Language eng
DOI 10.1016/j.cct.2019.105892
Indigenous content off
Field of Research 111502 Clinical Pharmacology and Therapeutics
11 Medical and Health Sciences
HERDC Research category C1 Refereed article in a scholarly journal
Persistent URL http://hdl.handle.net/10536/DRO/DU:30134726

Document type: Journal Article
Collections: Faculty of Health
School of Medicine
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